Review · secondary evidenceReview

Advancements in Functionalizable Metal-Organic Frameworks for Flexible Sensing Electronics

Xingliao Zhou, Xiaoliang Chen, Bo Yang, Sihai Luo, Meiling Guo, Ningli An, Hongmiao Tian, Xiangming Li, and Jinyou Shao · Advanced Functional Materials · 2025

This dossier represents secondary evidence: section summaries, claims and benchmarks are paraphrased for this database, not quoted. Check quantitative values against the linked primary study, and cite the review itself (10.1002/adfm.202501683) for its arguments.

8review sections
7material families
13review claims
21secondary benchmarks
40cited studies
7research gaps

Review scope

Systematically reviews functionalizable MOFs for flexible sensing electronics, covering MOF families, synthesis and modification methods, conductive MOF design, and applications in self-powered mechanical, gas, liquid-analyte and multi-target/mode sensors.

Coverage
1995–2025
Category
Review Sensor
Material scope
metal-organic frameworks · ZIF, MIL and UiO series MOFs · conductive MOFs · MOF composites on flexible substrates · MOF-derived materials for flexible sensing
Transport scope
proton conduction · electronic conduction · dual ionic-electronic conduction · electrical, capacitive, optical and photothermal sensing transduction
Application scope
self-powered mechanical sensing · flexible gas sensing · liquid analyte sensing · wearable health monitoring · multi-target and multi-mode sensors
Explicit exclusions
primary experimental recipes · non-MOF flexible sensors except as contextual comparators · exhaustive bibliography transcription
Source
1 · Abstract
Evidence role
Context, taxonomy and secondary benchmarking

Section map

The review’s argument is preserved as a navigable set of section summaries.

2.4-2.5. Conductive MOFs in Flexible Sensing

6-11

Distinguishes proton, electronic and dual conduction strategies and argues that intrinsic conductivity enables direct electrical readout in flexible sensors.

Relevance: Core · 7 · 2.4. Construction of Conductive MOFs

3.2-3.4. Gas, Liquid Analyte and Multi-Target/Mode Sensors

16-23

Covers MOF gas transduction, electrochemical liquid analyte sensing and multi-response sensor concepts for flexible platforms.

Relevance: Core · 16 · 3.2. Flexible Gas Sensors

1. Introduction

1-2

Frames flexible sensing requirements and motivates MOFs as tunable porous functional materials for curved, wearable and robotic devices.

Relevance: Core · 2 · 1. Introduction

2.3. Modification Methods of MOFs

6-8

Classifies MOF modification methods and explains why flexible sensors require compatibility, sensitivity, selectivity and dynamic stability.

Relevance: Core · 6 · 2.3. Modification Methods of MOFs · Figure 4

2. Metal-Organic Frameworks Overview

2-11

Introduces MOF structures, major families, synthesis routes, modification modes and conductive-MOF mechanisms.

Relevance: Core · 2 · 2. Metal-Organic Frameworks Overview

4. Conclusion and Outlooks

23-24

Synthesises advantages, remaining limits and future needs: better intrinsic conductivity, reduced signal crosstalk, selectivity against interferents, robust manufacturing and biocompatibility.

Relevance: Core · 23 · 4. Conclusion and Outlooks

3.1. Flexible Self-Powered Mechanical Sensors

12-15

Reviews triboelectric and piezoelectric MOF nanogenerator mechanisms and flexible self-powered mechanical sensor examples.

Relevance: Supporting · 12 · 3.1.1. Brief Description of Sensing Mechanism

2.2. Synthesis Method of MOFs

3-6

Summarises solvothermal/hydrothermal, template, mechanochemical, aerosol-assisted and seed-mediated approaches at strategy level.

Relevance: Core · 4 · 2.2. Synthesis Method of MOFs · Figure 3

Taxonomies

Classification systems are attributed to this review and are not treated as a global material registry.

Charge Carrier And Transport PathwayAuthor-proposed

Conductive MOF mechanism classes

The review distinguishes proton-conducting ligand/hydrogen-bond/water pathways, electronic metal/ligand/polymer pathways and MOFs combining both.

Categories: proton conduction · electronic conduction · dual ionic-electronic conduction

7 · 2.4. Construction of Conductive MOFs · Figures 6-7

Route For Adding Function Or Substrate IntegrationAuthor-proposed

MOF modification strategy taxonomy

Modification is divided into covalent surface/linker/node changes, non-covalent encapsulation or in situ growth, and sacrificial/template uses.

Categories: covalent modification · non-covalent modification · using MOF as template · using MOF as precursor

7 · 2.3. Modification Methods of MOFs · Figure 4

Framework Family And PropertiesAuthor-proposed

Common MOF series for flexible sensing context

The review organises common MOFs by framework series, emphasising ZIF chemical/thermal resilience, MIL porosity/breathing and UiO zirconium-node stability.

Categories: ZIF series · MIL series · UiO series

2 · 2.1. Brief Introduction of MOFs · Figure 2

Sensing Target And ModalityAuthor-proposed

Flexible MOF sensor application classes

The application taxonomy maps MOF function onto the review's four sensor classes, each with a separate mechanism section and examples.

Categories: self-powered mechanical sensors · gas sensors · liquid analyte sensors · multi-target/mode sensors

3 · Figure 1 caption · Figure 1

Preparation MethodAuthor-proposed

MOF synthesis route taxonomy

The review uses Figure 3 and section 2.2 to classify preparation strategies by reaction medium, templating, solid-state grinding, aerosol crystallisation and seed control.

Categories: solvothermal/hydrothermal · template · mechanochemical · aerosol-assisted · seed-mediated

5 · 2.2. Synthesis Method of MOFs · Figure 3

Material families

Review-defined families retain their representative materials and conduction descriptions.

2D conductive triphenylene/catecholate MOFs

2D Layered Conductive Framework

Planar conjugated MOFs based on HHTP, HITP or related ligands, commonly used for electronic or mixed response sensing.

Conduction: Porous conductive layers support electrical sensing and multi-target response through resistance/capacitance changes.

Representative materials: Cu3(HHTP)2 · Ni3(HITP)2 · Cu-HHTP · 2D Cu-BHT

Nodes / linkers: Cu · Ni · hexahydroxytriphenylene · hexaaminotriphenylene · benzenehexathiol

8 · 2.3. Modification Methods of MOFs · Figure 5d

MIL series MOFs

3D Porous Framework

Materials of Institute Lavoisier frameworks typically containing trivalent metal ions and high porosity.

Conduction: The review highlights proton-conductive functionalisation in MIL-68 and structural breathing in MIL-53.

Representative materials: MIL-101 · MIL-53 · MIL-68 · MIL-88A

Nodes / linkers: Fe · Al · Cr · In · carboxylate ligands · terephthalate derivatives

2 · 2.1. Brief Introduction of MOFs · Figure 2b-c

MOF/polymer and MOF/flexible-substrate composites

Thin Film, Fibre, Fabric, Hydrogel Or Flexible Composite

MOFs grown on, embedded in or compounded with flexible polymers, fabrics, carbon materials or 2D materials.

Conduction: Conductivity and mechanical integrity arise from conductive substrates, 2D materials, polymers, metal nanoparticles or conductive MOFs.

Representative materials: MOF-525/Ecoflex · ZIF-8 hydrogel · NiCAT@CNTF · Cu-TCA/TiNC · Ti3C2Tx@Cu3(HHTP)2

Nodes / linkers: Cu · Ni · Co · Zr · Zn · various MOF linkers · polymer matrices · carbon nanotube or MXene supports

6 · 2.3. Modification Methods of MOFs

Proton-conducting carboxylate/phosphonate MOFs

3D Framework

MOFs designed around ligand substitution, hydration or hydrogen-bond networks for proton transport.

Conduction: Proton conductivity is tuned by ligand replacement, hydration environments and dense hydrogen-bond networks.

Representative materials: PCMOF-2 · PCMOF2 1/2 · Zn5FDC · Zr/Hf-MOFs

Nodes / linkers: Zn · Zr · Hf · phenylsulfonic acid · phenylphosphonic acid · fluorene dicarboxylate

7 · 2.4. Construction of Conductive MOFs · Figure 6

Dual ionic-electronic conductive MOFs

3D Or Extended Conductive Framework

MOFs whose electronic transport is combined with proton or ionic transport pathways.

Conduction: Combines electron transfer through conjugated/redox linkers with proton transport via hydration, open sites or acid groups.

Representative materials: Cu3HHTT2 · TTF-phosphonate lanthanum MOF · CuthiaTRX

Nodes / linkers: Cu · La · tetraazanaphthotetraphene · tetrathiafulvalene-phosphonate · sulfur-containing truxene

10 · 2.4. Construction of Conductive MOFs · Figure 7d

UiO series MOFs

3D Porous Framework

Zirconium-node MOFs represented by UiO-66 with terephthalic acid ligands.

Conduction: Functional groups can enhance proton conductivity or gas response; UiO chemistry is emphasised for stability.

Representative materials: UiO-66 · UiO-66-Hf · UiO-66-NH2

Nodes / linkers: Zr · Hf · terephthalic acid · functionalised terephthalates

3 · 2.1. Brief Introduction of MOFs · Figure 2d

Zeolitic imidazolate frameworks

3D Porous Framework

Transition-metal imidazolate MOFs with zeolite-like structures.

Conduction: Usually valued for pore structure and chemical resilience rather than intrinsic high conductivity; often combined or modified for sensing.

Representative materials: ZIF-8 · ZIF-7 · ZIF-9 · ZIF-11 · ZIF-12

Nodes / linkers: Zn · transition metals · imidazole ligands · 2-methylimidazole

2 · 2.1. Brief Introduction of MOFs · Figure 2a

Synthesis strategies

Review-level synthesis principles remain separate from primary-study recipes.

Aerosol-assisted crystallisation

Continuous aerosol-assisted processing controls solvent evaporation and precursor residence time to improve crystallinity.

Claimed effects: Review states HKUST-1 crystals gained high crystallinity, clear facets and higher specific surface area.

Controlling variables: evaporation rate · residence time · precursor concentration · tube furnace conditions

Representative materials: HKUST-1

Caveat: The review does not quantify the specific-area improvement in the text.

5 · 2.2. Synthesis Method of MOFs · Figure 3e

Conductivity engineering in MOF frameworks

Conductive channels are introduced through pi-pi overlap, metal-ligand bond tuning, ligand substitution, hydration, metal-ion intercalation, conductive polymers or dual-conduction linkers.

Claimed effects: Enhances intrinsic electrical or protonic pathways, enabling direct signal readout in flexible sensing.

Controlling variables: ligand electronic structure · metal node · hydration environment · intercalated ion · conductive polymer incorporation · framework disorder

Representative materials: PCMOF2 1/2 · MIL-68-In derivatives · Zn5FDC · CuthiaTRX · Cu3HHTT2 · NU-1000 polymer composite

Caveat: Enhanced conductivity can introduce response cross-talk and interference, highlighted as an outlook issue.

10 · 2.5. Potential of Highly Conductive MOFs in Flexible Sensing

Covalent functionalisation and metal-node modification

Functional molecules, chemical groups, nanoparticles or metal sites are introduced at MOF active sites to tune response, stability or interface bonding.

Claimed effects: Can improve stability, interfacial bonding, gas/humidity responsiveness or catalytic/redox activity for liquid analytes.

Controlling variables: functional group · metal site · node versus linker modification · surface active-site density

Representative materials: Pd-modified MOF-1 · Cu-CTC · functional-group modified MOFs

Caveat: The review presents broad benefits; primary studies remain needed for specific chemistry-performance tradeoffs.

6 · 2.3. Modification Methods of MOFs · Figure 4b-c

In situ growth on flexible substrates

MOFs are grown directly on fabrics, polymers, electrodes or complex substrates to increase analyte contact and preserve flexible-substrate properties.

Claimed effects: Improves contact area, substrate integration, breathability or response speed in flexible devices.

Controlling variables: substrate chemistry · surface activation · growth density · MOF/substrate adhesion · substrate morphology

Representative materials: HKUST-1 on cotton · HKUST-1 on flexible electrode · Cu-HHTP on nanowire arrays

Caveat: Device durability under repeated deformation is identified later as a remaining manufacturing challenge.

6 · 2.3. Modification Methods of MOFs · Figure 5b-d

Mechanochemical synthesis

MOFs are formed using grinding or solid-state reactions, reducing solvent demand and improving synthesis efficiency.

Claimed effects: Review reports HKUST-1 prepared by grinding as water-stable compared with conventional hydrothermal HKUST-1.

Controlling variables: grinding time · solid reactants · liquid-assisted grinding additive · ambient conditions

Representative materials: HKUST-1 · MOF-199

Caveat: Scalability, defect distribution and crystallinity comparisons are not deeply analysed.

5 · 2.2. Synthesis Method of MOFs · Figure 3d

Seed-mediated phase control

Specific seeds introduced into precursor solution direct growth and suppress impurities of different MOF phases.

Claimed effects: Improves purity of synthesised MOF powders by avoiding phase impurities.

Controlling variables: seed identity · seed concentration · precursor composition · nucleation pathway

Representative materials: pure phase MOF

Caveat: The review treats this as a purity-control strategy rather than a full synthetic protocol.

6 · 2.2. Synthesis Method of MOFs · Figure 3f

Solvothermal/hydrothermal self-assembly

Metal salts and ligands react in solvent; the solvent acts as reaction medium and can gradually release active ligand groups to promote ordered framework growth.

Claimed effects: General route for forming MOF frameworks by controlled self-assembly.

Controlling variables: solvent · metal salt · ligand · reaction temperature · reaction time · ligand release rate

Representative materials: generic MOFs · hydrothermal MOF examples

Caveat: The review presents this at conceptual level and does not provide full recipes.

4 · 2.2. Synthesis Method of MOFs · Figure 3a-b

Template-assisted MOF synthesis

Soft or hard templates guide framework formation and are removed or transformed to leave desired porous structures.

Claimed effects: Enables porous structure control; H-MOF pore size was reported tunable by template amount.

Controlling variables: template type · template amount · surfactant or hard-template identity · removal conditions

Representative materials: H-MOF

Caveat: Template removal and residuals are not discussed in detail in this review.

5 · 2.2. Synthesis Method of MOFs · Figure 3c

Review claims

These are the review authors’ synthesis, not newly measured results.

Author InterpretationHigh supportCaveat

Conventional MOFs' poor conductivity limits their use in high-precision flexible mechanical, gas and ionic-environment sensing.

Evidence basis: review_reasoning

Caveat: The review discusses this generally; primary conductivity metrics vary by framework and device architecture.

6 · 2.3. Modification Methods of MOFs

DescriptiveMedium supportTransport Mechanism

Dual ionic-electronic conductive MOFs are emerging, with gas or hydration changing proton/electron pathways and creating new sensing response modes.

Evidence basis: multi_reference

Caveat: The review treats the area as recently reported and does not establish long-term stability.

10 · 2.4. Construction of Conductive MOFs

Consensus SummaryHigh supportTransport Mechanism

Electronic conduction in MOFs can be improved by metal-node choice, ion intercalation, conductive-polymer connection, amorphization and electric-field alignment.

Evidence basis: multi_reference

Caveat: Mechanisms and robustness vary across MOF classes; the review does not resolve measurement comparability.

10 · 2.4. Construction of Conductive MOFs · Figure 7

Author InterpretationHigh supportStructure Property Link

In situ MOF growth and surface functionalisation improve contact area, analyte access and substrate bonding in flexible sensors.

Evidence basis: multi_reference

Caveat: Manufacturing durability under repeated deformation remains an outlook concern.

6 · 2.3. Modification Methods of MOFs

Consensus SummaryHigh supportMeasurement Interpretation

MOF gas sensors translate adsorption and active-site interactions into changes in resistance/conductance, capacitance, fluorescence, spectrum or surface potential.

Evidence basis: multi_reference

Caveat: Optical mechanisms often require external acquisition equipment, which complicates integration.

16 · 3.2.1. Brief Description of Sensing Mechanism

Author InterpretationHigh supportApplication Relevance

Intrinsic conductivity allows MOF sensing units to be read accurately and quickly through electrical signals while retaining porous responsive properties.

Evidence basis: review_reasoning

Caveat: Electrical readout may increase cross-talk in multi-response devices.

10 · 2.5. Potential of Highly Conductive MOFs in Flexible Sensing

Consensus SummaryHigh supportMeasurement Interpretation

Flexible liquid-analyte MOF sensors usually rely on electrochemical mechanisms in which MOF active sites enrich/catalyse analytes and produce current, voltage, conductivity, capacitance or impedance changes.

Evidence basis: multi_reference

Caveat: Biological-fluid interference and selectivity still require primary-device validation.

18 · 3.3.1. Brief Description of Sensing Mechanism

Author InterpretationHigh supportCaveat

Commercial wearable MOF sensors require robust interface bonding, deformation-resistant manufacturing and attention to potential allergic or rejection reactions from organic ligands.

Evidence basis: review_reasoning

Caveat: Biocompatibility is raised as a concern, not systematically reviewed.

24 · 4. Conclusion and Outlooks

Consensus SummaryHigh supportDefinition Scope

MOFs are positioned as functionalizable porous frameworks whose size, shape, pore distribution and conductivity can be tuned for flexible sensing needs.

Evidence basis: multi_reference

Caveat: The review does not quantify tunability across all MOF families.

2 · 1. Introduction

Author InterpretationHigh supportApplication Relevance

MOFs' multiple response mechanisms enable multi-target or multi-mode flexible sensors without stacking complex structures and can reduce signal decoupling demands.

Evidence basis: multi_reference

Caveat: The outlook also notes increased conductivity can introduce interference between response mechanisms.

21 · 3.4.1. Brief Description of Sensing Mechanism

Consensus SummaryHigh supportTransport Mechanism

Proton-conducting MOFs can be designed through ligand replacement, functional-group engineering, hydration and hydrogen-bond networks.

Evidence basis: multi_reference

Caveat: The review reports selected examples, not a unified quantitative model for proton transport.

8 · 2.4. Construction of Conductive MOFs · Figure 6

Author InterpretationHigh supportCaveat

High-precision MOF sensing must differentiate target molecules from size-comparable interferents when porous structures interact with external substances.

Evidence basis: review_reasoning

Caveat: This is a review-level outlook statement rather than a resolved mechanism.

23 · 4. Conclusion and Outlooks

Consensus SummaryHigh supportApplication Relevance

Most MOF-based flexible nanogenerators reviewed use triboelectric mechanisms because porous MOFs provide high surface area and tunable surface properties.

Evidence basis: multi_reference

Caveat: Piezoelectric MOF examples exist but receive less emphasis.

12 · 3.1.1. Brief Description of Sensing Mechanism

Secondary benchmarks

Every row remains visibly secondary and links to a primary dossier only where the mapping is verified.

MaterialPropertyReported valueContext and qualityPrimary evidenceReview source
SecondaryBi2S3-MOF paper sensorH2S detection limit0.23 μm over 0–40 μm (as printed)Flexible multi-mode gas sensor with colour and thermal-imaging outputs; the review prints a 0–40 μm range
Text · Uncertain
No verified corpus mapping23 · 3.4.2. MOF-Based Flexible Multi-Target/Mode Sensors · Figure 12f
SecondaryCo- and Ni-doped MOF-74 on carbon clothmaximum output voltage4500 V and 2.84 mA cm-2Hybrid fabric used with diode in TENG manufacturing
Text · Rounded Reported
No verified corpus mapping12 · 3.1.2. MOF-Based Flexible Self-Powered Mechanical Sensors · Figure 8e
SecondaryTi3C2Tx@Cu3(HHTP)2 bionic smart skinexternal stimulus recognition accuracy97.6%Machine-learning-assisted pressure and NO2 gas response smart skin
Text · Exact Reported
No verified corpus mapping21 · 3.4.2. MOF-Based Flexible Multi-Target/Mode Sensors · Figure 12b
SecondaryCu3(HHTP)2 compositeelectronic conductivity increase under electric-field-regulated alignmentup to 5000 times that of the originalCu3(HHTP)2 dispersed in insulating oligomers with electric-field-regulated conductive-layer direction
Text · Rounded Reported
No verified corpus mapping10 · 2.4. Construction of Conductive MOFs
SecondaryCu-TCA/TiNC filmresistance change in NO124% resistance change in 50 ppm NO; maximum detection limit 140 ppbRoom-temperature flexible NO sensor in wide humidity range
Text · Exact Reported
No verified corpus mapping18 · 3.2.2. MOF-Based Flexible Gas Sensors · Figure 10f
SecondaryCuthiaTRXproton conductivityup to 10-2 S cm-1Sulfur-containing truxene-based EC-MOF
Text · Approximate
No verified corpus mapping8 · 2.4. Construction of Conductive MOFs · Figure 6d
SecondaryF-containing MOF/PDMS TENGpower density52 uW cm-2; 11 times greater than TENG without MOFKAUST-8/AlFFIVE-1-Ni in PDMS triboelectric pair with Al foil
Text · Rounded Reported
No verified corpus mapping12 · 3.1.2. MOF-Based Flexible Self-Powered Mechanical Sensors · Figure 8b
SecondaryFe-based MOFselectronic conductivity advantageat least 5 orders of magnitude higher conductivityComparison of 20 MOFs in four structural series
Text · Qualitative
research_02218 · 2.4. Construction of Conductive MOFs · Figure 7a
SecondaryMIL-101specific surface areamore than 4000 m2 g-1MIL series overview
Text · Approximate
No verified corpus mapping2 · 2.1. Brief Introduction of MOFs
Secondaryisostructural MIL-68-In MOFsproton conductivity10-4-10-3 S cm-1Five differently functionalised indium-based MIL-68 MOFs
Text · Range
No verified corpus mapping7 · 2.4. Construction of Conductive MOFs · Figure 6b
SecondaryMOF-525/Co-NPC/MXene composite fabricpeak power density25.7 W m-2Stretchable washable composite-coated TENG fabric
Text · Exact Reported
No verified corpus mapping15 · 3.1.2. MOF-Based Flexible Self-Powered Mechanical Sensors · Figure 9c
SecondaryMOF-5specific surface areamore than 3000 m2 g-1Historical MOF-5 framework example with H2BDC ligand and zinc nodes
Text · Approximate
No verified corpus mapping2 · 2.1. Brief Introduction of MOFs
SecondaryNi3HHTP2 nanocellulose sweat sensorvitamin C concentration range10-1190 um; correlation coefficient 0.9997; 1 mV working voltageWearable sweat sensor for vitamin C and uric acid
Text · Range
research_006919 · 3.3.2. MOF-Based Flexible Liquid Analytes Sensors · Figure 11b
SecondaryNi3(HITP)2-MSMC filmpressure sensitivity61.61 kPa-1 over 300 kPa; 20 ms response; 1 Pa detection limitFlexible pressure-temperature dual-function sensor
Text · Exact Reported
No verified corpus mapping21 · 3.4.2. MOF-Based Flexible Multi-Target/Mode Sensors · Figure 12a
SecondaryNi/Co bimetallic MOF nanosheet cortisol patchcortisol detection limit0.032 ng mL-1 over 0.1-100 ng mL-1Flexible sweat cortisol patch under mechanical deformation
Text · Exact Reported
No verified corpus mapping20 · 3.3.2. MOF-Based Flexible Liquid Analytes Sensors · Figure 11d
SecondaryNi/Co bimetallic MOF on cotton fabricglucose sensitivity105.2 and 23 uA mM-1 cm-2 over 0.04-3.13 and 3.63-8.28 mMFlexible electrode for enzyme-free glucose sensing
Text · Exact Reported
No verified corpus mapping19 · 3.3.2. MOF-Based Flexible Liquid Analytes Sensors · Figure 11c
SecondaryPCMOF2 1/2proton conductivity increase versus beta-PCMOF-2at least two orders of magnitude higherLigand substitution in PCMOF-2 family
Text · Qualitative
No verified corpus mapping7 · 2.4. Construction of Conductive MOFs · Figure 6a
SecondaryUiO-66-4F@PDMSmaximum power density38.7 W m-2Table 1 recent progress in MOF-based flexible nanogenerators and flexible sensors
Table · Exact Reported
No verified corpus mapping15 · 3.1.2. MOF-Based Flexible Self-Powered Mechanical Sensors · Table 1
SecondaryZIF-7/polyimide/ethyl cellulose TENGoutput voltage and currentup to 60 V and 1.1 uATENG comparison among ZIF-7, ZIF-9, ZIF-11 and ZIF-12
Text · Rounded Reported
No verified corpus mapping12 · 3.1.2. MOF-Based Flexible Self-Powered Mechanical Sensors · Figure 8a
SecondaryMe4BOPHY-1 in ZIF-8 fluorescent filmgas detection limit1.13 ppbFluorescent gas sensor; review also reports 3 s response and 19.78% molecular fluorescence efficiency
Text · Exact Reported
No verified corpus mapping16 · 3.2.2. MOF-Based Flexible Gas Sensors · Figure 10b
SecondaryZIF-8 nanofibrous matmaximum power density204.8 mW m-2Pressure/friction sensing entry in Table 1
Table · Exact Reported
No verified corpus mapping15 · 3.1.2. MOF-Based Flexible Self-Powered Mechanical Sensors · Table 1

Research gaps

Open questions are presented as review-author priorities, not conclusions from the primary database.

Wearable biocompatibility

Medium

Organic ligands in MOF frameworks may pose allergic or rejection concerns for users.

Proposed direction: Improve structure design and manufacturing to avoid adverse user reactions.

24 · 4. Conclusion and Outlooks

Commercial wearables

Medium

Technical and financial barriers still prevent wider commercial use of MOF-based wearable devices.

Proposed direction: Combine improved materials, manufacturing, lower costs and AI/ML-enhanced data processing for health monitoring.

24 · 4. Conclusion and Outlooks

MOF-substrate interfaces

Medium

Stable interface bonding between MOF sensitive materials and flexible substrates remains necessary for practical service life.

Proposed direction: Improve printing and substrate-integration processes that maintain MOF adhesion under deformation.

23 · 4. Conclusion and Outlooks

Intrinsic MOF conductivity

High

MOF conductivity remains far behind graphene, limiting direct electrical sensing and high-performance flexible devices.

Proposed direction: Develop better synthesis or modification procedures to improve intrinsic conductivity while preserving porosity.

23 · 4. Conclusion and Outlooks

Flexible-device manufacturing

High

Frequent deformation and friction can cause performance drift and shortened service life in flexible MOF sensors.

Proposed direction: Develop simple, efficient and stable sensor structures and manufacturing processes.

23 · 4. Conclusion and Outlooks

Molecular selectivity

High

Porous MOFs must distinguish target molecules from interfering molecules of comparable size to achieve high-precision sensing.

Proposed direction: Advance material design around pore chemistry, active sites and recognition mechanisms.

23 · 4. Conclusion and Outlooks

Response cross-talk

High

Higher conductivity provides richer response mechanisms but also creates more interference between sensing channels.

Proposed direction: Find methods to reduce signal crosstalk between different response mechanisms.

23 · 4. Conclusion and Outlooks

Cited-study map

Mappings show which printed review references have a verified counterpart in the frozen primary corpus.

Show 40 cited-study records
ReferenceStudyRole and contextCorpus mapping
Ref. 352020Title unavailablesecondary_benchmark · TENGReview cites this work for a fluorinated MOF/PDMS TENG with enhanced voltage, current and power density.Unmapped
Ref. 362024Title unavailablesecondary_benchmark · multi_target_sensorReview cites this smart-skin work for independent pressure and NO2 responses and machine-learning classification.Unmapped
Ref. 372023Title unavailabletable_benchmark · nanogeneratorTable 1 benchmark for UiO-66-4F@PDMS maximum power density.Unmapped
Ref. 432022Title unavailablesecondary_benchmark · liquid_analyte_sensorReview cites this wearable Ni3HHTP2 patch for vitamin C and uric acid sweat sensing.research_0069
Ref. 442021Title unavailablesecondary_benchmark · multi_target_sensorReview cites this Ni3(HITP)2-MSMC film for pressure-temperature dual sensing.Unmapped
Ref. 482022Title unavailablehistorical_context · mof_overviewReview cites this source while discussing MOF-5 as an early typical MOF structure.Unmapped
Ref. 692022Title unavailablemof_family · porosity_benchmarkReview cites this in Figure 2 for MIL-101 structure and SEM images.Unmapped
Ref. 862016Title unavailablemodification_strategyReview cites this Pd node modification example for heterostructure formation and catalytic activity.Unmapped
Ref. 902022Title unavailablesubstrate_integration · in_situ_growthReview cites this in situ self-growth on cotton fabric example.Unmapped
Ref. 912022Title unavailablesubstrate_integration · electrodepositionReview cites this in situ electrodeposition example for flexible liquid analyte sensing.Unmapped
Ref. 922021Title unavailablesubstrate_integration · gas_sensorReview cites this dense Cu-HHTP growth on nanowire arrays for resistive ammonia sensing.Unmapped
Ref. 932022Title unavailablemulti_response_sensor · actuatorReview cites this dual-response methanol-driven flexible actuator/sensor based on MIL-88A composite.Unmapped
Ref. 952024Title unavailableconductive_mof_contextReview cites this in arguing that highly conductive MOFs can address signal readout limits in sensing devices.Unmapped
Ref. 982018Title unavailableproton_conduction · secondary_benchmarkReview cites this for proton conductivity enhancement by ligand substitution in PCMOF materials.Unmapped
Ref. 992024Title unavailableproton_conduction · secondary_benchmarkReview cites this for differently functionalised isostructural MIL-68 MOFs with higher proton conductivity.Unmapped
Ref. 1032024Title unavailableproton_conduction · hydrationReview cites this for humidity-triggered proton conductivity through reversible water coordination.Unmapped
Ref. 1042024Title unavailableproton_conduction · secondary_benchmarkReview cites this sulfur-containing truxene MOF for high proton conductivity.Unmapped
Ref. 1082017Title unavailableelectronic_conduction · secondary_benchmarkReview cites this comparative study of activation energy and conductivity across 20 MOFs.research_0221
Ref. 1092017Title unavailableelectronic_conduction · intercalationReview cites this Li intercalation work for anisotropic electron hopping and adjustable conductivity.Unmapped
Ref. 1102017Title unavailableelectronic_conduction · polymer_connectionReview cites this conductive polymer connection at NU-1000 ligand sites for semiconducting-state control.Unmapped
Ref. 1112024Title unavailabledual_conduction · gas_responseReview cites this dual ionic-electronic conductive MOF with gas-modulated proton conductivity.research_0108
Ref. 1132024Title unavailableelectronic_conduction · field_alignment · secondary_benchmarkReview cites this electric-field-regulated Cu3(HHTP)2 composite conductivity enhancement.Unmapped
Ref. 1142025Title unavailabledual_conductionReview cites Souto group's dual-conductivity TTF-phosphonate lanthanum MOF.research_0051
Ref. 1332020Title unavailableTENG · secondary_benchmarkReview cites this comparison of ZIF MOFs as TENG triboelectric layers.Unmapped
Ref. 1342022Title unavailableTENG · MOF_derivedReview cites this MOF-derived Co-NPC/PVDF nanofiber TENG work.Unmapped
Ref. 1352024Title unavailableTENG · ligand_effectReview cites this bimetallic MOF ligand study for TENG performance changes.Unmapped
Ref. 1362024Title unavailableTENG · secondary_benchmarkReview cites this in situ Co/Ni-MOF-74 fabric TENG with high voltage/current density.Unmapped
Ref. 1392022Title unavailableTENG · secondary_benchmark · wearable_fabricReview cites this stretchable washable composite-coated fabric TENG.Unmapped
Ref. 1532024Title unavailabletable_benchmark · pressure_friction_sensorTable 1 benchmark for ZIF-8 nanofibrous mat pressure/friction sensing.Unmapped
Ref. 1642017Title unavailablegas_sensing_mechanism · conductive_mofReview cites this for oxidising/reducing gas effects on MOF conductivity.Unmapped
Ref. 1662018Title unavailablegas_sensing_mechanism · capacitanceReview cites this for capacitance-based gas-concentration sensing with MOFs.Unmapped
Ref. 1702024Title unavailablegas_sensor · fluorescence · secondary_benchmarkReview cites this ZIF-8 fluorescent film for gas sensing performance.Unmapped
Ref. 1732022Title unavailablegas_sensor · secondary_benchmarkReview cites this Cu-TCA/TiNC NO sensor with UV-tuned structure and resistance response.Unmapped
Ref. 1932024Title unavailableliquid_analyte_mechanismReview cites this for MOFs capturing analytes in solution because of porous structures.Unmapped
Ref. 1982022Title unavailableliquid_analyte_mechanism · glucoseReview cites this for metal-node catalysis of glucose oxidation in MOF liquid analyte sensing.Unmapped
Ref. 2012022Title unavailableliquid_analyte_sensor · sweat_sodiumReview cites this NiCAT@CNTF sodium sweat sensor and double-layer capacitance enhancement.Unmapped
Ref. 2022023Title unavailableliquid_analyte_sensor · secondary_benchmark · glucoseReview cites this flexible enzyme-free glucose sensor based on Ni/Co bimetallic MOF grown on cotton fabric.Unmapped
Ref. 2032023Title unavailableliquid_analyte_sensor · secondary_benchmark · cortisolReview cites this flexible cortisol patch using Ni/Co bimetallic MOF nanosheets.Unmapped
Ref. 2052024Title unavailablemulti_target_sensor · humidity_temperatureReview cites this CuCl2-doped MOF-303 humidity-temperature sensor.Unmapped
Ref. 2062025Title unavailablemulti_mode_sensor · secondary_benchmark · H2SReview cites this Bi2S3-MOF flexible sensor for dual color and thermal imaging H2S detection.Unmapped