Sensing Application — Ultrasmall Au(0) Inserted Hollow PCN-222 MOF for the High-Sensitive Detection of Estradiol

11 measurement groups · 41 results

Reported values remain attached to the sample, method, conditions, extraction quality and source location that produced them.

chronoamperometry and Cottrell analysis

Chronoamperometry

AuHPCN-222/GCE · Electrode

0.1 M PBS (pH 7.0), ED concentrations 0, 50.0, 100.0, 150.0 and 200.0 uM; slope of current versus t-1/2 analysed.

Geometry: AuHPCN-222/GCE
Context: target electrode
Measurement source: rendered page 5 / article p.4570 · Chronoamperometry · Figure 4b; Equation 6

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
chronoamperometric concentration linear dependence range	1 to 200 uM	—	—	Text Range	rendered page 5 / article p.4570 · Chronoamperometry · Figure 4b
ED diffusion coefficient from chronoamperometryMarked as a best value within this paper	7.45 x 10-6 cm2 s-1	0.00000745 cm2 s-1	—	Text Exact Reported	rendered page 5 / article p.4570 · Chronoamperometry · Figure 4b; Equation 6

cyclic voltammetry of estradiol oxidation

Voltammetry

AuHPCN-222/GCE · Electrode

50 uM ED in 0.1 M PBS (pH 7), scan rate 0.1 V s-1; comparison of bare GCE, HPCN-222/GCE, AuNP/GCE, AuSPCN-222 and AuHPCN-222.

Geometry: modified GCE sensor
Context: target electrode versus controls
Measurement source: rendered page 4 / article p.4569 · Electrocatalytic activity toward ED · Figure 3c

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
AuHPCN-222/GCE ED anodic current increase versus AuNP/GCE	1.45 times	1.45 fold	—	Text Exact Reported	rendered page 4 / article p.4569 · Electrocatalytic activity toward ED · Figure 3c
AuHPCN-222/GCE ED anodic current increase versus AuSPCN-222/GCE	1.2 times	1.2 fold	—	Text Exact Reported	rendered page 4 / article p.4569 · Electrocatalytic activity toward ED · Figure 3c
AuHPCN-222/GCE ED anodic current increase versus bare GCEMarked as a best value within this paper	3.2 times	3.2 fold	—	Text Exact Reported	rendered page 4 / article p.4569 · Electrocatalytic activity toward ED · Figure 3c
AuHPCN-222/GCE ED anodic current increase versus HPCN-222/GCE	1.5 times	1.5 fold	—	Text Exact Reported	rendered page 4 / article p.4569 · Electrocatalytic activity toward ED · Figure 3c
AuHPCN-222/GCE ED oxidation negative shift versus AuNP/GCEMarked as a best value within this paper	61 mV	61 mV	—	Text Exact Reported	rendered page 4 / article p.4569 · Electrocatalytic activity toward ED · Figure 3c

differential pulse voltammetry (DPV) calibration

Voltammetry

AuHPCN-222/GCE · Electrode

0.1 M PBS (pH 7), ED concentrations 0.01-220 uM. SI protocol: 0.37-0.73 V range, 0.004 V step, 0.05 V modulation amplitude, 0.2 s interval.

Geometry: AuHPCN-222/GCE
Context: target electrode
Measurement source: rendered page 5 / article p.4570 · Determination of ED · Figure 5; Equations 7-8

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
DPV low-range calibration R2	R2 = 0.977	0.977	—	Text Exact Reported	rendered page 5 / article p.4570 · Determination of ED · Equation 7
DPV low-range calibration slope	0.2631	0.2631 uA uM-1	—	Text Exact Reported	rendered page 5 / article p.4570 · Determination of ED · Equation 7
DPV high-range calibration R2Marked as a best value within this paper	R2 = 0.996	0.996	—	Text Exact Reported	rendered page 5 / article p.4570 · Determination of ED · Equation 8
DPV high-range calibration slope	0.0349	0.0349 uA uM-1	—	Text Exact Reported	rendered page 5 / article p.4570 · Determination of ED · Equation 8
first DPV linear detection range for ED	0.01-1 uM	—	—	Text Range	rendered page 1 / article p.4566 · Abstract · Figure 5b; Equation 7
second DPV linear detection range for EDMarked as a best value within this paper	1-220 uM	—	—	Text Range	rendered page 1 / article p.4566 · Abstract · Figure 5b; Equation 8
Table 2 overall linear range for AuHPCN-222/GCE	0.01-210 uM	—	—	Table Range	rendered page 6 / article p.4571 · Table 2 · Table 2
measured limit of detectionMarked as a best value within this paper	0.5 nM	0.0005 uM	—	Text Exact Reported	rendered page 5 / article p.4570 · Determination of ED · Table 2
first linear range sensitivityMarked as a best value within this paper	2.2 uA uM cm-2	2.2 uA uM cm-2	—	Text Exact Reported	rendered page 5 / article p.4570 · Determination of ED
second linear range sensitivity	0.3 uA uM cm-2	0.3 uA uM cm-2	—	Text Exact Reported	rendered page 5 / article p.4570 · Determination of ED

Laviron kinetic analysis

AuHPCN-222/GCE · Electrode

Electrode kinetics calculated from ED oxidation using Laviron equations; values tabulated in Table 1.

Geometry: AuHPCN-222/GCE
Context: target electrode
Measurement source: rendered page 5 / article p.4570 · Kinetics Results · Table 1

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
Laviron-derived active area AMarked as a best value within this paper	0.74 cm2	0.74 cm2	—	Table Exact Reported	rendered page 5 / article p.4570 · Kinetics Results · Table 1
surface-confined analyte amount Gamma_c	17.40 nM	17.4 nM	—	Table Exact Reported	rendered page 5 / article p.4570 · Kinetics Results · Table 1
electron transfer rate constant ksMarked as a best value within this paper	2.74 x 10-3 s-1	0.00274 s-1	—	Table Exact Reported	rendered page 5 / article p.4570 · Kinetics Results · Table 1
number of electrons transferred n	2.3	2.3	—	Table Exact Reported	rendered page 5 / article p.4570 · Kinetics Results · Table 1

pH-dependent CV/oxidation potential study

Voltammetry

AuHPCN-222/GCE · Electrode

pH varied from 3 to 9; ED oxidation potential and anodic current recorded.

Geometry: AuHPCN-222/GCE
Context: target electrode
Measurement source: rendered page 4 / article p.4569 · Electrocatalytic activity toward ED · Figure 3d

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
Ep versus pH regression R2	R2 = 0.997	0.997	—	Text Exact Reported	rendered page 4 / article p.4569 · Electrocatalytic activity toward ED · Figure 3d
Ep versus pH slope	-0.054 V pH-1	-0.054 V pH-1	—	Text Exact Reported	rendered page 4 / article p.4569 · Electrocatalytic activity toward ED · Figure 3d
optimum pH for ED oxidation currentMarked as a best value within this paper	pH 7	7 pH	—	Text Exact Reported	rendered page 4 / article p.4569 · Electrocatalytic activity toward ED · Figure 3d
pH study range	pH 3 to 9	—	—	Text Range	rendered page 4 / article p.4569 · Electrocatalytic activity toward ED · Figure 3d

standard-addition analysis of ED in pharmaceutical tablet

AuHPCN-222/GCE · Electrode

30 ED tablets (2 mg) ground and dissolved in 250 mL absolute ethanol; stock diluted with PBS pH 7 and analysed by standard addition with HPLC comparison.

Geometry: AuHPCN-222/GCE sensor
Context: target electrode applied to pharmaceutical sample
Measurement source: rendered page S-8 · Real sample analysis · Table S3

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
ED tablet standard-addition recovery	101.2%	101.2 %	—	SI Table Exact Reported	rendered page S-8 · Table S3 · Table S3

standard-addition analysis of ED in human urine

AuHPCN-222/GCE · Electrode

Human urine sample from Yangzhou University hospital stored at 4 C; 1 mL urine diluted 20 times with pH 7 PBS; standard addition analysed against HPLC comparison.

Geometry: AuHPCN-222/GCE sensor
Context: target electrode applied to real sample
Measurement source: rendered page S-8 · Real sample analysis · Table S2

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
real-sample analysis RSD upper limit	less than 3.5%	3.5 %	upper bound	Text Range	rendered page 6 / article p.4571 · Interference and Real Sample Analysis · Tables S2 and S3
urine sample 1 recovery at 0.10 uM added ED	102.0%	102 %	—	SI Table Exact Reported	rendered page S-8 · Table S2 · Table S2
urine sample 1 recovery at 10.00 uM added ED	99.97%	99.97 %	—	SI Table Exact Reported	rendered page S-8 · Table S2 · Table S2
urine sample 1 recovery at 1.00 uM added ED	101.6%	101.6 %	—	SI Table Exact Reported	rendered page S-8 · Table S2 · Table S2
urine sample 2 recovery at 0.10 uM added EDMarked as a best value within this paper	103.0%	103 %	—	SI Table Exact Reported	rendered page S-8 · Table S2 · Table S2
urine sample 2 recovery at 10.00 uM added ED	99.71%	99.71 %	—	SI Table Exact Reported	rendered page S-8 · Table S2 · Table S2
urine sample 2 recovery at 1.00 uM added ED	99.3%	99.3 %	—	SI Table Exact Reported	rendered page S-8 · Table S2 · Table S2

successive and between-electrode DPV repeatability/reproducibility

Voltammetry

AuHPCN-222/GCE · Electrode

10 successive DPV measurements in 0.05 mM ED solution at pH 7; five different AuHPCN-222/GCE electrodes for reproducibility.

Geometry: AuHPCN-222/GCE
Context: target electrode
Measurement source: rendered page 6 / article p.4571 · Repeatability and Reproducibility · Figure S3

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
repeatability RSD for 10 successive DPV measurementsMarked as a best value within this paper	0.78%	0.78 %	—	Text Exact Reported	rendered page 6 / article p.4571 · Repeatability and Reproducibility · Figure S3a
between-electrode reproducibility RSDMarked as a best value within this paper	0.85%	0.85 %	—	Text Exact Reported	rendered page 6 / article p.4571 · Repeatability and Reproducibility · Figure S3b

scan-rate-dependent cyclic voltammetry

Voltammetry

AuHPCN-222/GCE · Electrode

0.1 M PBS (pH 7.0) containing 0.05 mM ED; scan rates 10, 25, 50, 75, 100, 150 and 200 mV s-1.

Geometry: AuHPCN-222/GCE
Context: target electrode
Measurement source: rendered page 5 / article p.4570 · Electrode process by scan rate variation · Figure 4a

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
IED versus square-root scan-rate R2	R2 = 0.992	0.992	—	Text Exact Reported	rendered page 4 / article p.4569 · Electrode process by scan rate variation · Figure 4a
scan-rate range	0.01-0.2 V s-1	—	—	Text Range	rendered page 5 / article p.4570 · Electrode process by scan rate variation · Figure 4a
IED versus square-root scan-rate slope	23.108	23.108 uA (V s-1)-1/2	—	Text Exact Reported	rendered page 4 / article p.4569 · Electrode process by scan rate variation · Figure 4a

interference/selectivity recovery test

AuHPCN-222/GCE · Electrode

0.05 mM ED with inorganic species at 1000-fold and organic species at 300-fold concentrations; interferents included Na+, K+, Ca2+, Cl-, ascorbic acid, urea, dopamine, uric acid, tyramine, tryptamine, glucose, bisphenol A, atrazine and parathion.

Geometry: AuHPCN-222/GCE
Context: target electrode
Measurement source: rendered page 6 / article p.4571 · Interference and Real Sample Analysis · Figure S5

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
approximate selectivity recovery range across interferents	approximately 99.7-100.22% recovery	—	visual range read from bar chart	Visual Estimate Approximate	rendered page S-7 · Supporting Information · Figure S5

ambient-storage DPV stability/robustness

Voltammetry

AuHPCN-222/GCE · Electrode

Sensor kept at ambient temperature for 20 days with daily DPV of 0.05 mM ED (pH 7).

Atmosphere: ambient
Geometry: AuHPCN-222/GCE
Context: target electrode
Measurement source: rendered page 6 / article p.4571 · Repeatability and Reproducibility · Figure S4

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
ambient robustness duration	20 days	20 days	—	Text Exact Reported	rendered page 6 / article p.4571 · Repeatability and Reproducibility · Figure S4
robustness plot RSDMarked as a best value within this paper	R.S.D 0.08%	0.08 %	—	Figure Axis Exact Reported	rendered page S-7 · Supporting Information · Figure S4