Sensing Application — Glucose sensing performance of bimetallic MOFs CoFe-ZIF/CC for enzyme-free saliva sensor applications

8 measurement groups · 30 results

Reported values remain attached to the sample, method, conditions, extraction quality and source location that produced them.

Chronoamperometry glucose calibration

Chronoamperometry

Co0.95Fe0.05-ZIF/CC/GCE electrode · Electrode

CA response to successive glucose additions at 0.40 V in 0.10 M NaOH; GCE-based Co0.95Fe0.05-ZIF/CC sensor.

Temperature: room temperature
Geometry: Co0.95Fe0.05-ZIF/CC/GCE in three-electrode cell.
Context: Main composite electrode sensitivity and LOD.
Measurement source: 6-7 · 3.2 Glucose-Sensing Performance · Fig. 5a-b; Table 1

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
GCE high-range calibration equation from Fig. 5b	y3 = 103.90x + 108.10	—	plot annotation	Figure Axis Rounded Reported	7 · Figure · Fig. 5b
GCE low-range calibration equation from Fig. 5b	y1 = 129.10x + 6.85	—	plot annotation	Figure Axis Rounded Reported	7 · Figure · Fig. 5b
GCE mid-range calibration equation from Fig. 5b	y2 = 228.36x + 15.68	—	plot annotation	Figure Axis Rounded Reported	7 · Figure · Fig. 5b
GCE sensor glucose detection limitMarked as a best value within this paper	about 5 uM; abstract/conclusions state less than 5 uM	—	about/less than	Text Approximate	1,6 · Abstract; 3.2 Glucose-Sensing Performance
Best GCE sensor sensitivityMarked as a best value within this paper	3232.30 uA mM-1 cm-2 in 0.20-1.00 mM	—	—	Text Exact Reported	1,6 · Abstract; 3.2 Glucose-Sensing Performance · Fig. 5b; Table 1
GCE sensor sensitivity in high glucose range	1470.63 uA mM-1 cm-2 in 1.00-2.00 mM	—	—	Text Exact Reported	6 · 3.2 Glucose-Sensing Performance · Fig. 5b; Table 1
GCE sensor sensitivity in low glucose range	1827.25 uA mM-1 cm-2 in 0.005-0.20 mM	—	—	Text Exact Reported	6 · 3.2 Glucose-Sensing Performance · Fig. 5b; Table 1

Chronoamperometry glucose calibration

Chronoamperometry

Co0.95Fe0.05-ZIF/GCE electrode · Electrode

Control CA response for Co0.95Fe0.05-ZIF at 0.40 V; values reported from Fig. S9a-e.

Temperature: room temperature
Geometry: Co0.95Fe0.05-ZIF/GCE in three-electrode cell.
Context: Pristine bimetallic ZIF control.
Measurement source: 6 · 3.2 Glucose-Sensing Performance · Fig. S9a-e

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
Pristine Co0.95Fe0.05-ZIF high-range calibration equation from SI Fig. S9	y3 = 2.26E-2x + 23.36	—	plot annotation	Figure Axis Rounded Reported	7 · Figure S9 · Fig. S9e
Pristine Co0.95Fe0.05-ZIF low-range calibration equation from SI Fig. S9	y1 = 3.09E-2x + 2.87	—	plot annotation	Figure Axis Rounded Reported	7 · Figure S9 · Fig. S9e
Pristine Co0.95Fe0.05-ZIF mid-range calibration equation from SI Fig. S9	y2 = 3.81E-2x + 1.34	—	plot annotation	Figure Axis Rounded Reported	7 · Figure S9 · Fig. S9e
Pristine Co0.95Fe0.05-ZIF sensitivity high range	319.75 uA mM-1 cm-2 in 1.50-2.10 mM	—	—	Text Exact Reported	6 · 3.2 Glucose-Sensing Performance · Fig. S9
Pristine Co0.95Fe0.05-ZIF sensitivity low range	437.28 uA mM-1 cm-2 in 0.025-0.30 mM	—	—	Text Exact Reported	6 · 3.2 Glucose-Sensing Performance · Fig. S9
Pristine Co0.95Fe0.05-ZIF sensitivity mid range	538.60 uA mM-1 cm-2 in 0.30-1.50 mM	—	—	Text Exact Reported	6 · 3.2 Glucose-Sensing Performance · Fig. S9

Chronoamperometry potential optimisation

Chronoamperometry

Co0.95Fe0.05-ZIF/CC/GCE electrode · Electrode

Current response measured at 0.20, 0.30, 0.40 and 0.45 V for glucose additions; 0.40 V selected for subsequent CA.

Temperature: room temperature
Geometry: Three-electrode GCE cell.
Context: Composite electrode.
Measurement source: 5-6 · 3.2 Glucose-Sensing Performance · Fig. 4e-f

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
Appropriate operating-potential range	0.20-0.40 V	—	range	Text Range	5 · 3.2 Glucose-Sensing Performance · Fig. 4a
Optimised operating potential for CAMarked as a best value within this paper	0.40 V	—	—	Text Exact Reported	5 · 3.2 Glucose-Sensing Performance · Fig. 4e-f

Noninvasive PET glucose sensor CA calibration

Co0.95Fe0.05-ZIF/CC/PET saliva sensor · Electrode

Screen-printed PET three-electrode sensor with Co0.95Fe0.05-ZIF/CC; 30 uL glucose solution dropped on working region; glucose solutions from 0.005 mM to 2.10 mM prepared.

Temperature: room temperature
Geometry: PET three-electrode system coated with Co0.95Fe0.05-ZIF/CC and KOH-PVA gel.
Context: Application-level saliva sensor device.
Measurement source: 8-9 · 3.4 Glucose-sensing performance of non-enzymatic glucose sensor · Fig. 6b-c

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
PET sensor calibration equation from Fig. 6c	y = 3.81E-2x + 1.52	—	plot annotation	Figure Axis Rounded Reported	9 · Figure · Fig. 6c
PET sensor sensitivity	539.56 uA mM-1 cm-2	—	—	Text Exact Reported	8 · 3.4 Glucose-sensing performance · Fig. 6c
PET sensor reported linear range	from 0.025 uM to 2.00 mM	—	as printed; likely unit inconsistency	Text Uncertain	8 · 3.4 Glucose-sensing performance · Fig. 6c
PET sensor glucose detection limit	25 uM	—	—	Text Exact Reported	8 · 3.4 Glucose-sensing performance · Fig. 6c

PET sensor stability, repeatability and reproducibility

Co0.95Fe0.05-ZIF/CC/PET saliva sensor · Electrode

PET sensor retention after 30 days; RSD for 10 measurements on one PET sensor and for multiple devices.

Temperature: room temperature
Geometry: Co0.95Fe0.05-ZIF/CC/PET sensor.
Context: Application device durability statistics.
Measurement source: 8-9 · 3.4 Glucose-sensing performance · Fig. 6d-f

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
PET sensor repeatability RSD	less than 12.17% for 10 measurements	—	less than	Text Exact Reported	8 · 3.4 Glucose-sensing performance · Fig. 6e
PET sensor reproducibility RSD (figure annotation)	RSD <= 18.20%	—	less than or equal	Figure Axis Rounded Reported	9 · Figure · Fig. 6f
PET sensor reproducibility RSD (text)	less than 17.70% for five devices	—	less than	Text Exact Reported	8 · 3.4 Glucose-sensing performance · Fig. 6f
PET sensor 30-day retention	70.16% after 30 days	—	—	Text Exact Reported	8 · 3.4 Glucose-sensing performance · Fig. 6d

Saliva real-sample comparison with commercial blood glucose meter

Co0.95Fe0.05-ZIF/CC/PET saliva sensor · Electrode

Saliva from ten volunteers collected before meal and one hour after meal; blood glucose measured under same conditions for comparison.

Geometry: Co0.95Fe0.05-ZIF/CC saliva sensor with BIOSYS/mobile-phone readout.
Context: Real-sample application.
Measurement source: 8,10 · 3.5 Real sample detection · Fig. 7

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
Saliva sensor vs commercial blood glucose trend	Current response after a meal increased distinctly and was consistent with commercial blood glucose meter trends.	—	—	Text Qualitative	8,10 · 3.5 Real sample detection · Fig. 7b
Real-sample volunteer count	ten volunteers	—	—	Text Exact Reported	8 · 3.5 Real sample detection · Fig. 7b

CA selectivity/interference test

Co0.95Fe0.05-ZIF/CC/GCE electrode · Electrode

Successive addition of 500 uM glucose, urea, sucrose, L-serine, L-lysine, galactose, D-xylose, D-fructose and glucose.

Temperature: room temperature
Geometry: Co0.95Fe0.05-ZIF/CC/GCE.
Context: Composite electrode anti-interference performance.
Measurement source: 7-8 · 3.3 Selectivity, stability, reproducibility and repeatability · Fig. 5c

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
Selectivity interferent concentration	500 uM glucose and 500 uM interferents	—	—	Text Exact Reported	7 · 3.3 Selectivity · Fig. 5c
Selectivity result	Current response increases greatly after glucose; negligible responses for urea, sucrose, L-serine and L-lysine, slight responses for galactose, D-xylose and D-fructose.	—	—	Text Qualitative	7 · 3.3 Selectivity · Fig. 5c

Long-term stability, repeatability and reproducibility tests

Co0.95Fe0.05-ZIF/CC/GCE electrode · Electrode

GCE-based composite sensor retention after 30 days; RSD for 10 repeated measurements on one electrode and for ten Co0.95Fe0.05-ZIF/CC/GCE samples.

Temperature: room temperature
Geometry: Co0.95Fe0.05-ZIF/CC/GCE.
Context: Composite electrode durability statistics.
Measurement source: 7-8 · 3.3 Selectivity, stability, reproducibility and repeatability · Fig. 5d-f

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
GCE sensor repeatability RSD	less than 6.50% for 10 measurements on one electrode	—	less than	Text Exact Reported	8 · 3.3 Selectivity, stability, reproducibility and repeatability · Fig. 5e
GCE sensor reproducibility RSD	less than 6.43% for ten Co0.95Fe0.05-ZIF/CC/GCE samples	—	less than	Text Exact Reported	8 · 3.3 Selectivity, stability, reproducibility and repeatability · Fig. 5f
GCE sensor 30-day current-density retention	76.10% after 30 days	—	—	Text Exact Reported	7-8 · 3.3 Selectivity, stability, reproducibility and repeatability · Fig. 5d