Synthesis · Phthalocyanine-Based Two-Dimensional Conductive Metal-Organic Framework as Electrochemical Sensor for Highly Sensitive Detection of Nifedipine

3 structured synthesis routes

Completeness describes how fully the route could be reconstructed from the main article and supporting information.

Partial recipeSource: Main

Route 1: Drop Cast

3 · Preparation of modified electrodes

SolventsDMF

Atmosphereair drying after electrode cleaning; dried under infrared light after drop-casting

Substrate orientationpolished glassy carbon electrode

Work-upGCE polished with 0.3 and 0.05 um alumina, rinsed with ethanol and deionised water in an ultrasonic bath, dried in air; CoPc-Cu MOF suspension dropped on GCE and dried under infrared light.

Show 2 structured reagent records

Role	Reagent	Amount / concentration	Source
Other	CoPc-Cu MOF suspension	3 ul reported in electrode preparation; 5 ul selected as optimum in optimisation · 3 mg ml-1 in DMF	3 · Preparation of modified electrodes
Solvent	DMF	dispersion solvent	3 · Preparation of modified electrodes

Partial recipeSource: Main

Route 2: Solvothermal

3 · Synthesis of 2D CoPc-Cu MOF

Metal precursorsCoPc(OH)8; copper(II) trifluoroacetylacetonate, Cu(CF3acac)2

Linker precursors(2,3,9,10,16,17,23,24-octahydroxyphthalocyaninato)cobalt(II), [OH]8PcCo

SolventsDMF; water

AdditivesNH3.H2O

Atmospherenot stated

Temperature120

Time36

Work-upAfter cooling to room temperature, separated by centrifugation, washed several times with DMF, water, and acetone, and dried under vacuum.

Activationvacuum drying; no separate porosity activation reported

Show 5 structured reagent records

Role	Reagent	Amount / concentration	Source
Linker	CoPc(OH)8 / [OH]8PcCo	104 mg; 0.15 mmol · dissolved in 81 ml DMF	3 · Synthesis of 2D CoPc-Cu MOF
Solvent	DMF	81 ml plus 9 ml	3 · Synthesis of 2D CoPc-Cu MOF
Base	NH3.H2O	6.6 ml; 89 mmol	3 · Synthesis of 2D CoPc-Cu MOF
Solvent	water	90 ml · dilution solvent	3 · Synthesis of 2D CoPc-Cu MOF
Metal Source	Cu(II)(CF3acac)2 / Cu(CF3acac)2	109 mg; 0.30 mmol · in 9 ml DMF	3 · Synthesis of 2D CoPc-Cu MOF

Vague recipeSource: Main

Route 3: Drop Cast

3 · Preparation of modified electrodes

Linker precursorsCoPc(OH)8 / CoPc control

SolventsDMF

Substrate orientationpolished glassy carbon electrode

Work-upPrepared by the same GCE drop-casting procedure as CoPc-Cu MOF/GCE.

Show 1 structured reagent record

Role	Reagent	Amount / concentration	Source
Other	CoPc	not stated · not stated	3 · Preparation of modified electrodes