Synthesis · A Sensing Platform Based on Ni/Mn Bimetal-Organic Framework for Electrochemical Detection of Osimertinib

2 structured synthesis routes

Completeness describes how fully the route could be reconstructed from the main article and supporting information.

Complete recipeSource: Main

p003 · Fabrication of the Modified GCE

Metal precursorsNi/Mn-MOF powder already synthesised

Linker precursorsTPA in Ni/Mn-MOF component

SolventsDMF suspension; ethanol/water cleaning solution; deionised-water rinse

Additivesalumina powder for polishing

Atmosphereambient air, not explicitly stated

Temperatureroom temperature

Substrate orientationglassy carbon electrode surface

Work-upGCE polished with alumina, cleaned in ethanol/water, coated with 10 uL suspension, dried at room temperature and rinsed with deionised water.

Activation15 consecutive CV cycles from 0 to 0.5 V at 0.02 V/s in 0.1 M NaOH.

Scalability contextElectrode-scale drop-cast coating.

Show 4 structured reagent records

Role	Reagent	Amount / concentration	Source
Other	Ni/Mn-MOF powder	0.5 mg · 1 mg mL-1 in DMF	p003 · Fabrication of the Modified GCE
Solvent	DMF	0.5 mL	p003 · Fabrication of the Modified GCE
Electrolyte	NaOH	0.1 M	p003 · Fabrication of the Modified GCE
Additive	alumina powder	Not specified	p003 · Fabrication of the Modified GCE

Complete recipeSource: Main

p002-p003 · Synthesis of Ni/Mn-MOF · Scheme 1

Metal precursorsMnCl2 (0.05 g); Ni(NO3)2.6H2O (0.1 g)

Linker precursorsterephthalic acid, TPA (0.06 g)

Solventsethylene glycol (10 mL); DMF (16 mL)

Atmospherenot reported; sealed Teflon-lined autoclave

Temperature150

Time6

Work-upCooled to room temperature; green powder rinsed with ethanol and DMF.

ActivationDried overnight at 50 C.

Scalability contextOne-pot solvothermal batch; autoclave size and yield not reported.

Show 5 structured reagent records

Role	Reagent	Amount / concentration	Source
Linker	TPA	0.06 g	p002-p003 · Synthesis of Ni/Mn-MOF · Scheme 1
Metal Source	MnCl2	0.05 g	p002-p003 · Synthesis of Ni/Mn-MOF · Scheme 1
Metal Source	Ni(NO3)2.6H2O	0.1 g	p002-p003 · Synthesis of Ni/Mn-MOF · Scheme 1
Solvent	ethylene glycol (EG)	10 mL	p002-p003 · Synthesis of Ni/Mn-MOF · Scheme 1
Solvent	DMF	16 mL	p002-p003 · Synthesis of Ni/Mn-MOF · Scheme 1