Li W., Ma C., Song Y. et al. · Nanotechnology · 2020 · 185605
Open a family to keep every result attached to its sample, method and conditions.
Paraphrased for this database from the authors’ stated interpretations — never quoted verbatim — and kept separate from reported measurements.
The sandwich immunosensor detects CEA over 0.001-80 ng ml-1 with a 0.2 pg ml-1 detection limit and acceptable reproducibility, selectivity, stability and serum recovery.
Caveat: SI optimisation details were supplied for pH, incubation time and material concentration; no Figure S5 was present in the supplied SI.
1; 8-10 · Abstract; 3.2.3-3.5 · Figures 3,5,6; Tables 1,2 · Linked to 10 structured results
The paper does not report intrinsic bulk electrical conductivity, thermoelectric performance, porosity values, or fitted charge-transfer resistance values for Ce-MoF; conductive evidence is electrochemical/application-level.
Caveat: The main text claims good electrical conductivity for the nanocomposite, but reports no S cm-1 or equivalent transport measurement.
2; 7-8 · 1; 3.2-3.3 · Figures 3,4 · Linked to 3 structured results
HA coating provides -COOH and -OH groups and biocompatibility, enabling Ag NP/HRP loading on Ce-MoF and supporting H2O2 catalysis.
Caveat: Main text provides morphology/FTIR evidence but no quantitative surface loading.
2; 4 · 1; 3.1 · Figure 2 · Linked to 4 structured results
Ag NPs and HRP co-catalyse H2O2 reduction, giving the largest amperometric current response for Ce-MoF@HA/Ag-HRP modified GCE.
Caveat: Figure 4 provides the order visually and textually, but exact current magnitudes are not reported.
8 · 3.3 · Figure 4 · Linked to 1 structured result
Au NPs on GCE accelerate electron transfer and reduce interface resistance, improving the platform for Ab1 attachment.
Caveat: The Ret trend is qualitative because fitted EIS values are not tabulated.
2; 7 · 1; 3.2.2 · Figure 3C · Linked to 2 structured results
Names and aliases are kept exactly within the paper’s own identity model.
| Material | Composition | Structure context | Source |
|---|---|---|---|
| Ce-metal organic framework (Ce-MoF) | Ce-BTC metal-organic framework from Ce(NO3)3.6H2O and H3BTCcerium nodes from cerium nitrate hexahydrate · 1,3,5-benzenetricarboxylic acid (H3BTC) | unknown · PristineSheet-like Ce-MoF morphology; EDS shows C, O and Ce. No crystallographic topology or PXRD peak list is reported in the main text. | 2-3 · 1; 2.3; 3.1 · Figure 2A,A-1,B |
| Ce-MoF@HA | Ce-BTC MOF coated with hyaluronic acidcerium nodes from Ce-MoF · H3BTC framework linker plus hyaluronic acid coating bearing -COOH and -OH groups | unknown · CompositeHA-coated Ce-MoF nanocomposite; TEM indicates a uniform HA film on Ce-MoF. | 3-4 · 2.4; 3.1 · Figure 2C,D,H |
| Ce-MoF@HA/Ag | Ce-MoF@HA loaded with silver nanoparticlescerium nodes in Ce-MoF plus Ag nanoparticles · H3BTC framework linker and hyaluronic acid coating | unknown · CompositeAg-loaded HA-coated Ce-MoF; TEM shows Ag NPs on the Ce-MoF@HA surface and EDS shows Ce, O and Ag. | 3-5 · 2.5; 3.1 · Figure 2E,F,I |
| MOF-Ce@HA/Ag-HRP-Ab2 nanoprobe | Ce-MoF@HA/Ag conjugated with horseradish peroxidase and anti-CEA secondary antibodycerium nodes in Ce-MoF plus Ag nanoparticles · H3BTC framework linker, hyaluronic acid coating, HRP protein and Ab2 biomolecule | unknown · CompositeBioconjugated Ce-MoF@HA/Ag nanoprobe for sandwich electrochemical immunosensing. | 2-4 · 1; 2.6 · Figure 1 |
| glassy carbon electrode platform and non-MOF controls | GCE, Au NP/GCE, and biomolecule-modified GCE controlsnone for bare GCE; Au nanoparticles for Au-modified GCE controls · none | unknown · Model SystemElectrode controls used to interpret electrochemical assembly and catalysis. | 3; 6-7 · 2.7; 3.2.2 · Figure 3B,C |
| Au/Ab1/BSA/CEA/MOF-Ce@HA/Ag-HRP-Ab2 modified GCE immunosensor | glassy carbon electrode + Au NPs + Ab1 + BSA + CEA + MOF-Ce@HA/Ag-HRP-Ab2cerium nodes in Ce-MoF, Ag nanoparticles, and Au nanoparticles on GCE · H3BTC, hyaluronic acid, antibodies, BSA and HRP | unknown · CompositeLayered sandwich electrochemical immunosensor assembled on glassy carbon electrode. | 3-4 · 2.7; 2.8 · Figure 1 |
Sample form, processing state and composition status define the context for measurements.
| Sample | Form and role | Processing and geometry | Source |
|---|---|---|---|
| Au NPs modified GCEresearch_0577__mat__mat_gce_platform | Electrode · Pristine Control · Composite | Au NPs drop-cast on GCE as electron-transfer/Ab1 platform.glassy carbon electrode | 3; 6-7 · 2.7; 3.2.2 · Figure 3B,C |
| bare GCE controlresearch_0577__mat__mat_gce_platform | Electrode · Pristine Control · Model | Polished with alumina, washed with ethanol and deionized water, dried at room temperature.4 mm glassy carbon electrode | 3 · 2.7 |
| Ce-MoF@HA/Ag modified GCEresearch_0577__mat__mat_ce_mof_ha_ag | Electrode · Composite Sample · Composite | Ce-MoF@HA/Ag material modified onto bare GCE for amperometric comparison.glassy carbon electrode | 7-8 · 3.3 · Figure 4 |
| MoF-Ce@HA/Ag-HRP-Ab2 nanoproberesearch_0577__mat__mat_ce_mof_ha_ag_hrp_ab2 | Unknown · Target Sample · Composite | EDC/NHS-activated Ab2 and HRP incubated with BSA and Ce-MoF@HA/Ag at 4 C, centrifuged and washed with PBS. | 3 · 2.6 |
| Ce-MoF@HA/Ag-HRP modified GCEresearch_0577__mat__mat_ce_mof_ha_ag_hrp_ab2 | Electrode · Composite Sample · Composite | Ce-MoF@HA/Ag-HRP material modified onto bare GCE for H2O2 amperometric catalytic comparison.glassy carbon electrode | 7-8 · 3.3 · Figure 4 |
| Ce-MoF@HA/Ag productresearch_0577__mat__mat_ce_mof_ha_ag | Powder · Composite Component · Composite | Ce-MoF@HA treated with AgNO3 and NaBH4 in water/ice bath, stood at 4 C, washed with deionized water. | 3-4 · 2.5; 3.1 · Figure 2E,F,I |
| Ce-MoF@HA modified GCEresearch_0577__mat__mat_ce_mof_ha | Electrode · Composite Sample · Composite | Ce-MoF@HA material modified onto bare GCE for amperometric comparison.glassy carbon electrode | 7-8 · 3.3 · Figure 4 |
| Ce-MoF@HA productresearch_0577__mat__mat_ce_mof_ha | Powder · Composite Component · Composite | Ce-MoF dispersed with HA in DMF-water, sonicated, stirred overnight, washed with DMF and acetone, dried at 70 C.HA film about 5 nm on Ce-MoF by TEM | 3-4 · 2.4; 3.1 · Figure 2C,D,H |
| Ce-MoF milky white precipitateresearch_0577__mat__mat_ce_mof | Powder · Pristine Control · Pristine Framework | Water-bath precipitated, washed with ethanol and deionized water, dried at 70 C for 12 h. | 3 · 2.3 |
| sandwich CEA immunosensor on GCEresearch_0577__mat__mat_immunosensor_gce | Electrode · Target Sample · Composite | GCE polished, Au NPs drop-cast, Ab1/BSA/CEA sequentially incubated, and MoF-Ce@HA/Ag-HRP-Ab2 nanoprobe incubated for sandwich assembly.4 mm glassy carbon electrode | 3-4 · 2.7; 2.8 · Figure 1 |