Sensing Application — Two-dimensional π-conjugated metal-organic framework with high electrical conductivity for electrochemical sensing

10 measurement groups · 34 results

Reported values remain attached to the sample, method, conditions, extraction quality and source location that produced them.

CV pH optimisation

Voltammetry

Cu3(HHTP)2/GCE modified electrode · Electrode

100 uM dopamine in PBS buffer; pH 6.0, 6.1, 6.2, 6.3, 6.4, 6.5, 7.0 and 7.5; scan rate 100 mV/s.

Geometry: Cu3(HHTP)2/GCE working electrode
Context: composite sensing electrode containing pristine Cu3(HHTP)2
Measurement source: p004-p005 (journal pp.525-526) · 3.3 Optimization of condition · Figure 4

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
Optimal pH for DA detectionMarked as a best value within this paper	pH 6.3	—	—	Text Exact Reported	p005 (journal p.526) · 3.3 Optimization of condition · Figure 4
Approximate maximum pH-optimisation currentMarked as a best value within this paper	approximately 0.285 mA near pH 6.3	—	visual estimate, about +/-0.01 mA	Figure Axis Approximate	p004 (journal p.525) · 3.3 Optimization of condition · Figure 4

Cyclic voltammetry (CV) selectivity test

Voltammetry

Cu3(HHTP)2/GCE modified electrode · Electrode

10 mM ascorbic acid, 0.10 mM dopamine, and blank PBS on Cu3(HHTP)2/GCE at 100 mV/s.

Geometry: Cu3(HHTP)2/GCE working electrode
Context: composite sensing electrode containing pristine Cu3(HHTP)2
Measurement source: p004 (journal p.525) · 3.2 Electrochemical sensing of DA · Figure 3

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
AA interference response	no signal response to 10 mM AA	—	—	Text Qualitative	p004 (journal p.525) · 3.2 Electrochemical sensing of DA · Figure 3
DA response in selectivity CV	obvious current signal for 0.10 mM DA	—	—	Text Qualitative	p004 (journal p.525) · 3.2 Electrochemical sensing of DA · Figure 3

Differential pulse voltammetry (DPV)

Voltammetry

Cu3(HHTP)2/GCE modified electrode · Electrode

Dopamine concentrations 50 nM, 500 nM, 5 uM, 20 uM, 30 uM, 40 uM, 50 uM, 60 uM, 90 uM, 150 uM and 200 uM on Cu3(HHTP)2/GCE at room temperature.

Temperature: room temperature
Geometry: Cu3(HHTP)2/GCE working electrode
Context: composite sensing electrode containing pristine Cu3(HHTP)2
Measurement source: p005 (journal p.526) · 3.4 Quantitative analysis of DA · Figure 6

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
Dopamine detection limitMarked as a best value within this paper	5.1 nM at S/N = 3	0.0051 uM	—	Text Exact Reported	p005 (journal p.526) · 3.4 Quantitative analysis of DA · Figure 6
Linear calibration R2Marked as a best value within this paper	R2 = 0.9994 (from Figure 6 inset)	—	visual read from rendered inset	Figure Axis Approximate	p005 (journal p.526) · 3.4 Quantitative analysis of DA · Figure 6 inset
DA linear concentration range lower boundMarked as a best value within this paper	5.0 x 10^-8 M	0.00005 mM	—	Text Exact Reported	p005 (journal p.526) · 3.4 Quantitative analysis of DA · Figure 6
DA linear concentration range upper boundMarked as a best value within this paper	2.0 x 10^-4 M	0.2 mM	—	Text Exact Reported	p005 (journal p.526) · 3.4 Quantitative analysis of DA · Figure 6
Approximate DPV peak current at 200 uM DA	approximately 16.5 uA at 2.0 x 10^-4 M DA	—	visual estimate, about +/-0.5 uA	Figure Axis Approximate	p005 (journal p.526) · 3.4 Quantitative analysis of DA · Figure 6

Electrode-to-electrode reproducibility

Cu3(HHTP)2/GCE modified electrode · Electrode

Current response of 0.10 mM dopamine in PBS measured with five independently prepared modified electrodes.

Geometry: five Cu3(HHTP)2/GCE working electrodes
Context: composite sensing electrode containing pristine Cu3(HHTP)2
Measurement source: p005-p006 (journal pp.526-527) · 3.5 Stability and reproducibility

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
Five-electrode reproducibility RSD	3.41 (reported; below 5%)	—	—	Text Exact Reported	p006 (journal p.527) · 3.5 Stability and reproducibility

Dopamine determination in human serum

Cu3(HHTP)2/GCE modified electrode · Electrode

DA determination in human serum and spiked samples; Table S1 reports baseline concentration 0.24 uM, additions 0.1/0.2/0.4 uM, found values, recoveries and RSDs.

Geometry: Cu3(HHTP)2/GCE working electrode
Context: composite sensing electrode containing pristine Cu3(HHTP)2
Measurement source: SI p003 · Determination of DA in real sample · Table S1

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
Human-serum spiked recovery lower bound	99.5%	—	—	Text Range	p006 (journal p.527) · 3.6 Determination of DA in a real sample · Table S1 referenced
Human-serum spiked recovery upper bound	105%	—	—	Text Range	p006 (journal p.527) · 3.6 Determination of DA in a real sample · Table S1 referenced
Sample 1 DA spike added	0.1 uM	—	—	SI Table Exact Reported	SI p003 · Determination of DA in real sample · Table S1
Sample 1 Human-serum DA concentration	0.24 uM	—	—	SI Table Exact Reported	SI p003 · Determination of DA in real sample · Table S1
Sample 1 DA found	0.345 uM	—	—	SI Table Exact Reported	SI p003 · Determination of DA in real sample · Table S1
Sample 1 DA spike recovery	105 %	—	—	SI Table Exact Reported	SI p003 · Determination of DA in real sample · Table S1
Sample 1 DA determination RSD	4.08 %	—	—	SI Table Exact Reported	SI p003 · Determination of DA in real sample · Table S1
Sample 2 DA spike added	0.2 uM	—	—	SI Table Exact Reported	SI p003 · Determination of DA in real sample · Table S1
Sample 2 Human-serum DA concentration	0.24 uM	—	—	SI Table Exact Reported	SI p003 · Determination of DA in real sample · Table S1
Sample 2 DA found	0.439 uM	—	—	SI Table Exact Reported	SI p003 · Determination of DA in real sample · Table S1
Sample 2 DA spike recovery	99.5 %	—	—	SI Table Exact Reported	SI p003 · Determination of DA in real sample · Table S1
Sample 2 DA determination RSD	3.44 %	—	—	SI Table Exact Reported	SI p003 · Determination of DA in real sample · Table S1
Sample 3 DA spike added	0.4 uM	—	—	SI Table Exact Reported	SI p003 · Determination of DA in real sample · Table S1
Sample 3 Human-serum DA concentration	0.24 uM	—	—	SI Table Exact Reported	SI p003 · Determination of DA in real sample · Table S1
Sample 3 DA found	0.642 uM	—	—	SI Table Exact Reported	SI p003 · Determination of DA in real sample · Table S1
Sample 3 DA spike recovery	102 %	—	—	SI Table Exact Reported	SI p003 · Determination of DA in real sample · Table S1
Sample 3 DA determination RSD	3.76 %	—	—	SI Table Exact Reported	SI p003 · Determination of DA in real sample · Table S1

Comparator CV against HKUST-1/GCE and ZIF-8/GCE

Voltammetry

Cu3(HHTP)2/GCE modified electrode · Electrode

0.10 mM dopamine on Cu3(HHTP)2/GCE, HKUST-1/GCE and ZIF-8/GCE; SI Figure S2.

Geometry: MOF-modified GCEs
Context: target electrode versus comparator MOF electrodes
Measurement source: SI p002 · Supporting Information · Figure S2

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
Relative sensitivity versus HKUST-1/GCE and ZIF-8/GCEMarked as a best value within this paper	Cu3(HHTP)2/GCE showed the highest sensitivity	—	—	Text Qualitative	p004 (journal p.525) · 3.2 Electrochemical sensing of DA · Figure S2 referenced

Comparator cyclic voltammetry (CV)

Voltammetry

HKUST-1/GCE · Electrode

0.10 mM dopamine on HKUST-1/GCE in SI Figure S2.

Geometry: HKUST-1/GCE working electrode
Context: comparator MOF-modified GCE
Measurement source: SI p002 · Supporting Information · Figure S2

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
HKUST-1/GCE comparator dopamine response	HKUST-1/GCE shows a much lower CV response than Cu3(HHTP)2/GCE in SI Figure S2	—	—	Visual Estimate Qualitative	SI p002 · Supporting Information · Figure S2

Comparator cyclic voltammetry (CV)

Voltammetry

ZIF-8/GCE · Electrode

0.10 mM dopamine on ZIF-8/GCE in SI Figure S2.

Geometry: ZIF-8/GCE working electrode
Context: comparator MOF-modified GCE
Measurement source: SI p002 · Supporting Information · Figure S2

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
ZIF-8/GCE comparator dopamine response	ZIF-8/GCE shows a much lower CV response than Cu3(HHTP)2/GCE in SI Figure S2	—	—	Visual Estimate Qualitative	SI p002 · Supporting Information · Figure S2

Stability test by repeated current response measurement

Cu3(HHTP)2/GCE modified electrode · Electrode

Stored at room temperature; measured current response of 0.10 mM dopamine in PBS once per day for 2 weeks.

Temperature: room temperature
Geometry: Cu3(HHTP)2/GCE working electrode
Context: composite sensing electrode containing pristine Cu3(HHTP)2
Measurement source: p005 (journal p.526) · 3.5 Stability and reproducibility

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
Two-week stability RSD	2.15%	—	—	Text Exact Reported	p005 (journal p.526) · 3.5 Stability and reproducibility

Performance comparison table

Cu3(HHTP)2/GCE modified electrode · Electrode

Table 1 compares linear range and detection limit for Cu3(HHTP)2/GCE against literature modified electrodes.

Geometry: Cu3(HHTP)2/GCE working electrode
Context: this-work composite sensing electrode
Measurement source: p006 (journal p.527) · 3.4 Quantitative analysis of DA · Table 1

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
Table 1 Cu3(HHTP)2/GCE linear range lower boundMarked as a best value within this paper	0.00005 mM	5e-8 M	—	Table Exact Reported	p006 (journal p.527) · Table 1 · Table 1
Table 1 Cu3(HHTP)2/GCE linear range upper boundMarked as a best value within this paper	0.2 mM	0.0002 M	—	Table Exact Reported	p006 (journal p.527) · Table 1 · Table 1
Table 1 Cu3(HHTP)2/GCE detection limitMarked as a best value within this paper	0.0051 uM	5.1 nM	—	Table Exact Reported	p006 (journal p.527) · Table 1 · Table 1