Bhardwaj S.K., Sharma A.L., Bhardwaj N. et al. · Sensors and Actuators, B: Chemical · 2017 · 10-17
Open a family to keep every result attached to its sample, method and conditions.
Paraphrased for this database from the authors’ stated interpretations — never quoted verbatim — and kept separate from reported measurements.
The antibody-TCNQ-Cu3(BTC)2 SPE provides conductometric PSA detection over the clinically relevant 0.1-100 ng/mL range with 0.06 ng/mL LOD and acceptable serum recovery.
Caveat: Sensing is an application result on a biofunctionalised composite electrode; not an intrinsic bulk transport property of the pristine MOF.
7 · 4 Conclusions · Linked to 10 structured results
TCNQ doping makes the Cu3(BTC)2 surface hydrophobic enough for effective physical adsorption of anti-PSA antibodies.
Caveat: Contact-angle images are in SI Fig. S2; values are taken from the main text.
4 · 3.3 Contact angle measurements · Fig. S2 · Linked to 4 structured results
TCNQ infiltration does not disrupt the crystalline Cu3(BTC)2 framework, while an additional low-angle XRD peak indicates guest binding to open metal sites.
Caveat: XRD patterns are in SI Fig. S3; the rendered SI was inspected, but the numerical peak position is taken from the main text rather than digitised from the plot.
4 · 3.4 Structural and morphological studies · Fig. S3 · Linked to 1 structured result
The BET surface area drop from 730 to 200 m2/g after TCNQ treatment is interpreted as sufficient loading of TCNQ in Cu3(BTC)2 open sites.
Caveat: N2 isotherms are in SI Fig. S4; BET surface areas are taken from the main text rather than digitised from the plotted isotherms.
4 · 3.4 Structural and morphological studies · Fig. S4 · Linked to 2 structured results
TCNQ doping introduces charge-transfer pathways in Cu3(BTC)2 through coordination/electron-transfer interactions with copper sites, producing solid-state electrical conductance.
Caveat: Mechanism is inferred from spectroscopy and literature-supported charge-transfer chemistry; no direct carrier-mobility measurement is reported.
3 · 3.1 Mechanism of TCNQ doping in Cu3(BTC)2 · Linked to 10 structured results
Names and aliases are kept exactly within the paper’s own identity model.
| Material | Composition | Structure context | Source |
|---|---|---|---|
| anti-PSA antibody immobilised TCNQ-Cu3(BTC)2Browse family: HKUST-1 / Cu₃(BTC)₂ | antibody-TCNQ-Cu3(BTC)2Cu nodes of TCNQ-doped Cu3(BTC)2 · BTC, TCNQ, physically adsorbed anti-PSA antibody | 3D · CompositeBiofunctionalised TCNQ-Cu3(BTC)2 thin-film electrode, with antibody immobilisation evidenced by UV-vis, FTIR and Raman signatures. | 2 · 2.3 Immobilization of anti-PSA antibodies on TCNQ-Cu3(BTC)2 |
| Cu3(BTC)2 copper metal-organic frameworkBrowse family: HKUST-1 / Cu₃(BTC)₂ | Cu3(BTC)2Cu(II) paddlewheel/open copper sites · BTC; trimesic acid/H3BTC | 3D · PristineCu-BTC/HKUST-1-type crystalline porous MOF; crystallinity agrees with literature XRD. | 2 · 2.1 Materials and equipment |
| TCNQ-doped Cu3(BTC)2Browse family: HKUST-1 / Cu₃(BTC)₂ | TCNQ-Cu3(BTC)2Cu(II)/Cu(I)-accessible Cu nodes with TCNQ coordination at open metal sites · BTC plus infiltrated 7,7,8,8-tetracyanoquinodimethane (TCNQ) | 3D · CompositeTCNQ-infiltrated Cu3(BTC)2 charge-transfer adduct retaining MOF crystallinity. | 4 · 3.1 Mechanism of TCNQ doping in Cu3(BTC)2 |
Sample form, processing state and composition status define the context for measurements.
| Sample | Form and role | Processing and geometry | Source |
|---|---|---|---|
| antibody-TCNQ-Cu3(BTC)2-SPEresearch_0544__mat__mat_antibody_tcnq_cu_btc | Electrode · Target Sample · Composite | TCNQ-Cu3(BTC)2-SPE incubated with 10 uL of 1 ug/mL anti-PSA in PBS pH 7.2 for 1 h; blocked with 0.01% Tween 20; washed and stored at 4 C.custom-made gold screen printed electrode | 2 · 2.3 Immobilization of anti-PSA antibodies on TCNQ-Cu3(BTC)2 |
| activated Cu3(BTC)2 powderresearch_0544__mat__mat_cu_btc | Powder · Pristine Control · Pristine Framework | Activated powder used for N2 sorption; pre-heated to 190 C for guest removal in spectroscopy context. | 4 · 3.2 UV-vis, FTIR, and Raman studies |
| Cu3(BTC)2 thin film on gold SPEresearch_0544__mat__mat_cu_btc | Electrode · Pristine Control · Pristine Framework | Sequential dipping grown film; dried/activated at 190 C for 90 min.custom-made gold screen printed electrode (working area 7.1 mm2) | 2 · 2.2 Synthesis of Cu3(BTC)2 thin films and their doping with TCNQ |
| TCNQ-Cu3(BTC)2 sorption sampleresearch_0544__mat__mat_tcnq_cu_btc | Powder · Target Sample · Doped | TCNQ-doped Cu3(BTC)2 sample used for N2 sorption comparison. | 4 · 3.4 Structural and morphological studies · Fig. S4 |
| 24 h TCNQ-Cu3(BTC)2 SPEresearch_0544__mat__mat_tcnq_cu_btc | Electrode · Target Sample · Doped | Cu3(BTC)2 SPE soaked in saturated TCNQ solution in CH2Cl2 for 24 h; dried under vacuum.custom-made gold screen printed electrode | 5 · 3.5 Application of antibody-TCNQ-Cu3(BTC)2 SPEs · Fig. 5 |
| 48 h TCNQ-Cu3(BTC)2 SPEresearch_0544__mat__mat_tcnq_cu_btc | Electrode · Target Sample · Doped | Cu3(BTC)2 SPE soaked in saturated TCNQ solution in CH2Cl2 up to 48 h; dried under vacuum.custom-made gold screen printed electrode | 2 · 2.2 Synthesis of Cu3(BTC)2 thin films and their doping with TCNQ |
| TCNQ-Cu3(BTC)2 SPE incubation-time seriesresearch_0544__mat__mat_tcnq_cu_btc | Electrode · Target Sample · Doped | Cu3(BTC)2 thin films incubated with TCNQ for 0-60 h; 0 h row is the undoped baseline within the same incubation experiment.custom-made gold screen printed electrode | 10 · Supplementary information · Table S1 |