Sensing Application — Laccase-inspired bi-amino acid MOFs with high substrate affinity: Catalytic deposition induced “signal-down” electrochemical response towards PD-L1

4 measurement groups · 17 results

Reported values remain attached to the sample, method, conditions, extraction quality and source location that produced them.

PD-L1 sandwich sensor on gold electrode · Electrode

Interferents at 10-fold concentration: His, glucose, ascorbic acid, BSA, IgG, Siglec-15, compared with PD-L1.

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
Interferent impedance response range	about 580-750 ohm for blank, His, glucose, AA, BSA, IgG, Siglec-15	—	error bars shown	Figure Axis Range	8 · 3.5 · Fig. 6C
PD-L1 selectivity responseMarked as a best value within this paper	about 1750 ohm	—	error bar shown	Figure Axis Approximate	7 · 3.5 · Fig. 6C

PD-L1 sandwich sensor on gold electrode · Electrode

EIS variation measured under optimised conditions for PD-L1 concentrations 0.5-200 ng/mL.

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
PD-L1 calibration intercept	2149.73	—	—	Text Exact Reported	8 · 3.5 · Fig. 6B
PD-L1 calibration R2	0.990	—	—	Text Exact Reported	8 · 3.5 · Fig. 6B
PD-L1 calibration slope	1288.26	—	—	Text Exact Reported	8 · 3.5 · Fig. 6B
PD-L1 detection range lower bound	0.5 ng/mL	—	—	Text Exact Reported	8 · 3.5 · Fig. 6B
PD-L1 detection range upper bound	200 ng/mL	—	—	Text Exact Reported	8 · 3.5 · Fig. 6B
PD-L1 limit of detection reported in abstract	0.12 ng/mL	—	—	Text Exact Reported	1 · Abstract
PD-L1 limit of detectionMarked as a best value within this paper	0.11 ng/mL (S/N = 3)	—	S/N = 3	Text Exact Reported	8 · 3.5 · Fig. 6B

PD-L1 sandwich sensor on gold electrode · Electrode

PD-L1 added to 10-fold diluted serum and measured under optimised conditions.

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
Serum spike found concentration at 25 ng/mL added	24.53 ng/mL	—	—	Table Exact Reported	7 · 3.6 · Table 1
Serum spike recovery at 25 ng/mL added	98.12%	—	RSD 3.09%	Table Exact Reported	7 · 3.6 · Table 1
Serum spike found concentration at 2.5 ng/mL added	2.72 ng/mL	—	—	Table Exact Reported	7 · 3.6 · Table 1
Serum spike recovery at 2.5 ng/mL added	108.80%	—	RSD 6.85%	Table Exact Reported	7 · 3.6 · Table 1
Serum spike found concentration at 50 ng/mL added	49.25 ng/mL	—	—	Table Exact Reported	7 · 3.6 · Table 1
Serum spike recovery at 50 ng/mL added	98.50%	—	RSD 5.15%	Table Exact Reported	7 · 3.6 · Table 1

PD-L1 sandwich sensor on gold electrode · Electrode

SPR angle changes during stepwise construction of PD-L1 biosensor.

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
SPR angle change after DA/ODA deposition	125 mdeg	—	—	Text Exact Reported	6 · 3.2 · Fig. 3C-D
SPR DA/ODA signal relative to PD-L1 signal	2.6 times	—	—	Text Exact Reported	6 · 3.2 · Fig. 3C-D