Primary studyCore evidenceThin Film Device

Electrochemical deposition of Cu metal-organic framework films for the dual analysis of pathogens

Sun Z., Peng Y., Wang M. et al. · Analytical Chemistry · 2020

4materials
6samples
3synthesis routes
17measurements
38results
4claims and caveats

Evidence map

Open a family to keep every result attached to its sample, method and conditions.

Author interpretations and caveats

Paraphrased for this database from the authors’ stated interpretations — never quoted verbatim — and kept separate from reported measurements.

Application RelevanceSupport assessment: High

The DNA/AuNPs/Cu-MOF biosensor detects S. aureus both indirectly through MNase in supernatant and directly through aptamer recognition of cells.

Caveat: Application evidence is for S. aureus ATCC 6538 and spiked urine/PBS tests, not clinical specimens.

main p.6, article p.8999-p.9000 · Conclusions · Linked to 4 structured results

Application RelevanceSupport assessment: Medium

The platform is selective against E. coli and L. monocytogenes in the reported PBS tests.

Caveat: Selectivity values are graphical estimates from SI Figure S5; exact currents are not tabulated.

main p.6, article p.8999 · Performance of the Biosensor · Figure S5 · Linked to 3 structured results

Composite RoleSupport assessment: High

AuNP decoration further promotes electron transfer and provides Au-S binding sites for aptamer loading on the Cu-MOF film.

Caveat: AuNP loading amount is not quantified.

main p.4, article p.8997 · Feasibility of the Biosensor · Figure S1 · Linked to 2 structured results

Structure Property LinkSupport assessment: High

Electrodeposited Cu-MOF films lower the Fe(CN)6 interfacial impedance relative to bare GCE and improve electron-transfer behaviour.

Caveat: The paper does not report intrinsic electronic conductivity in S/cm; evidence is electrochemical charge-transfer resistance and DPV current.

main p.4, article p.8997 · Feasibility of the Biosensor · Figure 2 · Linked to 3 structured results

Material identities

Names and aliases are kept exactly within the paper’s own identity model.

MaterialCompositionStructure contextSource
AuNPs/Cu-MOF composite filmNot specifiedCu-MOF copper nodes plus electrodeposited/reduced gold nanoparticles on the MOF surface. · H3BTC / 1,3,5-benzenetricarboxylate in the Cu-MOF component3D · CompositeComposite Cu-MOF film decorated with Au nanoparticles; SEM shows rough MOF surfaces surrounded by many nanoparticles.main p.3, article p.8997 · Characterization of MOF Films · Figure 1B
bare glassy carbon electrode controlCunknown · Model SystemNon-MOF electrode control used for EIS/DPV comparison.main p.3, article p.8996 · Treatment and Modification of the Electrode
electrodeposited Cu-MOF thin filmBrowse family: HKUST-1 / Cu₃(BTC)₂Cu-BTC framework, commonly Cu3(BTC)2; exact formula not explicitly statedCopper paddle-wheel nodes with Cu2+/Cu+ redox-active sites. · H3BTC / 1,3,5-benzenetricarboxylate3D · PristineCrystalline Cu-MOF with paddle-wheel-shaped metal corners connected by BTC linkers; XRD pattern of synthesized film is consistent with simulated Cu-MOF.main p.3, article p.8997 · Characterization of MOF Films · Figure 1
DNA/AuNPs/Cu-MOF biosensor interfaceNot specifiedCu-MOF copper nodes plus Au nanoparticles · H3BTC / 1,3,5-benzenetricarboxylate; thiolated S. aureus aptamer immobilised via Au-S bonds3D · CompositeAptamer-conjugated AuNPs/Cu-MOF composite film on GCE, blocked with 6-mercapto-1-hexanol.main p.2, article p.8995 · Introduction · Scheme 1

Sample register

Sample form, processing state and composition status define the context for measurements.

Show 6 sample records
SampleForm and roleProcessing and geometrySource
AuNPs/Cu-MOF/GCE electroderesearch_0754__mat__aunps_cu_mofElectrode · Composite Sample · CompositeAuNPs reduced in situ on the Cu-MOF surface at -0.5 V for 30 s.Cu-MOF film on glassy carbon electrodemain p.3, article p.8996 · Treatment and Modification of the Electrode
bare GCEresearch_0754__mat__bare_gce_modelElectrode · Model System · ModelPolished with alumina slurry, sonicated in ethanol and distilled water, rinsed and dried with nitrogen.glassy carbon electrode, 3 mm diametermain p.3, article p.8996 · Treatment and Modification of the Electrode
Cu-MOF/GCE electroderesearch_0754__mat__cu_btc_mofElectrode · Pristine Control · Pristine FrameworkElectrodeposited Cu-MOF film dried at 50 deg C.glassy carbon electrode · thin film; thickness not reportedmain p.3, article p.8996 · Treatment and Modification of the Electrode
DNA/AuNPs/Cu-MOF/GCE after S. aureus cell captureresearch_0754__mat__dna_aunps_cu_mofElectrode · Target Sample · CompositeBiosensor incubated with S. aureus cells for direct aptamer recognition.DNA/AuNPs/Cu-MOF film on glassy carbon electrodemain p.2, article p.8995 · Introduction · Scheme 1
DNA/AuNPs/Cu-MOF/GCE biosensorresearch_0754__mat__dna_aunps_cu_mofElectrode · Composite Sample · CompositeAuNPs/Cu-MOF/GCE incubated with thiolated S. aureus aptamer and blocked with MCH.AuNPs/Cu-MOF film on glassy carbon electrodemain p.3, article p.8996 · Biosensor Fabrication
DNA/AuNPs/Cu-MOF/GCE after S. aureus supernatant exposureresearch_0754__mat__dna_aunps_cu_mofElectrode · Target Sample · CompositeBiosensor incubated with S. aureus supernatant; MNase digests surface DNA aptamer.DNA/AuNPs/Cu-MOF film on glassy carbon electrodemain p.2, article p.8995 · Introduction · Scheme 1