Synthesis · Multifunctional coordination polymers based on copper with modified nucleobases, easily modulated in size and conductivity

6 structured synthesis routes

Completeness describes how fully the route could be reconstructed from the main article and supporting information.

Partial recipeSource: Main

Route 1: Other

3 · Materials and methods

Metal precursorspreformed CP1

Linker precursorspreformed CP1

Solventsnone reported for vapour exposure

Additivesiodine vapour

Atmosphereambient temperature and pressure

Temperatureambient

Time0-24

Oxidant / reductantIodine vapour used as p-type oxidative dopant

Work-upNo post-doping workup reported.

Show 2 structured reagent records

Role	Reagent	Amount / concentration	Source
Oxidant	iodine vapor	not reported	3 · Materials and methods
Other	CP1	not reported	3 · Materials and methods

Complete recipeSource: Main

Route 2: Other

3 · 2.2. Nanoprocessing of CP1 via top-down approach

Metal precursorspreformed CP1 crystals

Linker precursorspreformed CP1 crystals

Solvents3 mL acetone

Additivesultrasound bath processing

Atmosphereambient; not otherwise specified

Time1

Substrate orientationSiO2 substrate used only for SEM deposition

Work-upSuspension after 1 h sonication sampled before centrifugation; aliquot deposited on SiO2 for SEM.

Scalability contextPart of the top-down nanoprocessing route; final supernatant route gives 55% nanoprocessed material.

Show 2 structured reagent records

Role	Reagent	Amount / concentration	Source
Other	CP1 crystals	1.5 mg, ca. 2 mm	3 · 2.2. Nanoprocessing of CP1 via top-down approach
Solvent	acetone	3 mL	3 · 2.2. Nanoprocessing of CP1 via top-down approach

Complete recipeSource: Main

Route 3: Other

3 · 2.2. Nanoprocessing of CP1 via top-down approach

Metal precursorspreformed CP1 crystals

Linker precursorspreformed CP1 crystals

Solvents3 mL acetone

Atmosphereambient; not otherwise specified

Time1

Substrate orientationSiO2 substrate used only for SEM deposition

Work-upSonicated suspension centrifuged at 3000 rpm for 2 min; suspension and supernatant aliquots deposited on SiO2.

Scalability context55% of the initial material was nanoprocessed according to the main text.

Show 2 structured reagent records

Role	Reagent	Amount / concentration	Source
Other	CP1 crystals	1.5 mg, ca. 2 mm	3 · 2.2. Nanoprocessing of CP1 via top-down approach
Solvent	acetone	3 mL	3 · 2.2. Nanoprocessing of CP1 via top-down approach

Complete recipeSource: Main

Route 4: Solvothermal

3 · 2.1. Synthesis of CP1

Metal precursorsCu(NO3)2.3H2O (0.1 g, 0.41 mmol)

Linker precursorsthymine-1-acetic acid (0.152 g, 0.82 mmol); 4,4'-bpy (0.065 g, 0.41 mmol); oxalate forms in situ

Solvents18 mL MilliQ water

Atmospheresealed glass reactor; atmosphere not specified

Temperature140

Time72

Oxidant / reductantCu(II) nitrate; oxalate generated in situ from carboxyl groups under acidic solvothermal conditions

Work-upSupernatant removed under vacuum; turquoise crystals separated manually from dark-blue co-crystals.

ActivationDried/worked up under vacuum; no activation protocol reported.

Scalability context60% yield reported for manually separated turquoise CP1 crystals.

Show 4 structured reagent records

Role	Reagent	Amount / concentration	Source
Metal Source	Cu(NO3)2.3H2O	0.1 g, 0.41 mmol	3 · 2.1. Synthesis of CP1
Linker	thymine-1-acetic acid (TAcOH)	0.152 g, 0.82 mmol	3 · 2.1. Synthesis of CP1
Linker	4,4'-bpy	0.065 g, 0.41 mmol	3 · 2.1. Synthesis of CP1
Solvent	water MilliQ	18 mL	3 · 2.1. Synthesis of CP1

Complete recipeSource: Main

Route 5: Solvothermal

3 · 2.3. Synthesis of CP2

Metal precursorsCu(NO3)2.3H2O (100 mg, 0.41 mmol)

Linker precursorsUracil-1-acetic acid (141 mg, 0.82 mmol); 4,4'-bpy (65 mg, 0.41 mmol); oxalate forms in situ

Solvents18 mL water

Atmospheresolvothermal reactor; atmosphere not specified

Temperature120

Time72

Oxidant / reductantCu(II) nitrate; oxalate generated in situ under acidic solvothermal conditions

Work-upLight-blue crystals dried under vacuum after cooling.

ActivationDried under vacuum; no separate activation protocol reported.

Show 4 structured reagent records

Role	Reagent	Amount / concentration	Source
Metal Source	Cu(NO3)2.3H2O	100 mg, 0.41 mmol	3 · 2.3. Synthesis of CP2
Linker	Uracil-1-acetic acid (UAcOH)	141 mg, 0.82 mmol	3 · 2.3. Synthesis of CP2
Linker	4,4'-bpy	65 mg, 0.41 mmol	3 · 2.3. Synthesis of CP2
Solvent	water	18 mL	3 · 2.3. Synthesis of CP2

Complete recipeSource: Main

Route 6: Solvothermal

3 · 2.4. Synthesis of CP3

Metal precursorsaqueous solution (1 mL) of Cu(NO3)2.H2O (100 mg, 0.41 mmol)

Linker precursorsthymine-1-acetic acid (76 mg, 0.41 mmol); 4,4'-bpy (64 mg, 0.41 mmol)

Solvents12 mL ethanol plus 1 mL aqueous copper nitrate solution

Atmospheresolvothermal glass reactor; atmosphere not specified

Temperature140

Time72

Oxidant / reductantEthanol solvent implicated as reducing agent for Cu(II) to Cu(I).

Work-upYellow crystals filtered off and dried in vacuum.

ActivationDried in vacuum; no separate activation protocol reported.

Scalability context41% yield reported.

Show 4 structured reagent records

Role	Reagent	Amount / concentration	Source
Metal Source	Cu(NO3)2.H2O	100 mg, 0.41 mmol in 1 mL aqueous solution	3 · 2.4. Synthesis of CP3
Linker	thymine-1-acetic acid (TAcOH)	76 mg, 0.41 mmol	3 · 2.4. Synthesis of CP3
Linker	4,4'-bpy	64 mg, 0.41 mmol	3 · 2.4. Synthesis of CP3
Solvent	ethanol	12 mL	3 · 2.4. Synthesis of CP3