Huang W., Xu Y., Wang Z. et al. · Talanta · 2022 · 123612
Open a family to keep every result attached to its sample, method and conditions.
Paraphrased for this database from the authors’ stated interpretations — never quoted verbatim — and kept separate from reported measurements.
The Au-NPs/Cu-HHTP-NSs/GCE sensor provides sensitive H2O2 detection with 5.6 nM LOD, 188.1 uA cm-2 mM-1 sensitivity, 3 s response and broad linear range.
Caveat: Performance is for the specific modified electrode under PBS/amperometric conditions.
1, 7 · Abstract; 3.3. Electrochemical sensing performances · Fig. 4d-f · Linked to 4 structured results
Au-NPs/Cu-HHTP-NSs/GCE distinguishes colon cancer cells from normal colon cells by larger fMLP-stimulated H2O2 current responses in SW-48 and HCT-116 than NCM-460.
Caveat: Cell work is an application demonstration with specific cell lines and fMLP stimulation, not a clinical validation study.
8 · 3.4. Live cells detection · Fig. 5 · Linked to 4 structured results
SI kinetic fitting supports prominent peroxidase-like activity of Au-NPs/Cu-HHTP-NSs, with Km = 0.3947 mM and Vmax = 10.5x10-5 M min-1 for TMB oxidation.
Caveat: Kinetic constants are for the reported TMB/H2O2 assay conditions and should not be generalised to all substrates.
10-12 · Figure S11; Table S1 · Table S1 · Linked to 2 structured results
The composite electrode shows good anti-interference behaviour, reproducibility and four-week stability for H2O2 sensing.
Caveat: Interference result is qualitative from the article text; no exact percentage response to each interferent was provided.
7 · 3.3. Electrochemical sensing performances · Fig. 4g-i · Linked to 3 structured results
Exposed oxygen atoms on Cu-HHTP-NSs act as anchoring sites for high-density ultrafine Au nanoparticles without agglomeration.
Caveat: Anchoring-site assignment relies on spectroscopy and morphology, not atomically resolved bonding measurements.
1, 6 · Abstract; 3.3. Electrochemical sensing performances · Fig. 1g; Fig. 2b · Linked to 3 structured results
Transition from bulk Cu-HHTP to ultrathin nanosheets and Au-NP decoration lowers electrode charge-transfer resistance and improves electrocatalytic performance.
Caveat: EIS is measured on modified GCE electrodes and should not be treated as intrinsic single-material conductivity.
6 · 3.3. Electrochemical sensing performances · Fig. 4a-b · Linked to 4 structured results
SDS acts as a barrier agent that reduces layer stacking and weakens interlayer interactions, enabling ultrathin large Cu-HHTP nanosheets.
Caveat: Mechanistic statement is author interpretation supported by morphology comparison, not a direct kinetic proof.
3 · 3.1. Characterization · Scheme 1; Fig. 1 · Linked to 3 structured results
Names and aliases are kept exactly within the paper’s own identity model.
| Material | Composition | Structure context | Source |
|---|---|---|---|
| Au-NPs/Cu-HHTP-NSs nanohybridBrowse family: Cu₃(HHTP)₂ / Cu–HHTP | Au nanoparticles on Cu-HHTP-NSs; approximately 6 wt% Au by ICP-MSCu-O4 nodes in Cu-HHTP plus metallic Au nanoparticles · HHTP linker in Cu-HHTP nanosheets | 2D · CompositeComposite of ultrathin conductive Cu-HHTP nanosheets decorated with high-density ultrafine Au nanoparticles; Au (111) and (200) peaks observed. | 1, 3-5 · Abstract; Characterization of Au-NPs/Cu-HHTP-NSs · Fig. 1g-i; Fig. 2a |
| Cu-HHTP conductive metal-organic frameworkBrowse family: Cu₃(HHTP)₂ / Cu–HHTP | Cu-HHTP; HHTP = 2,3,6,7,10,11-hexahydroxytriphenylene; exact empirical stoichiometry not statedCu-O4 square-planar coordination nodes · HHTP (2,3,6,7,10,11-hexahydroxytriphenylene) | 2D · PristineTwo-dimensional conductive MOF with layer-stacked nanosheet or bulk morphology; PXRD planes (100), (200), (210), (220) and (112) retained with SDS-assisted nanosheet synthesis. | 2-4 · Introduction; Results and discussion · Fig. 2a |
Sample form, processing state and composition status define the context for measurements.
| Sample | Form and role | Processing and geometry | Source |
|---|---|---|---|
| Au-NPs/Cu-HHTP-NSsresearch_0797__mat__au_cu_hhtp | Nanosheet · Composite Sample · Composite | HAuCl4-treated Cu-HHTP-NSs; centrifuged, washed, freeze-dried and activated. | 2-5 · Synthesis; Characterization · Fig. 1g-i; Fig. 2 |
| Au-NPs/Cu-HHTP-NSs/GCEresearch_0797__mat__au_cu_hhtp | Electrode · Target Sample · Composite | 5 uL of Au-NPs/Cu-HHTP-NSs suspension drop-cast on GCE and dried in air.glassy carbon electrode (3 mm) with Nafion/isopropanol suspension | SI text · Preparation of Au-NPs/Cu-HHTP-NSs modified electrode |
| Au-NPs/Cu-HHTP-NSs with higher HAuCl4 amountresearch_0797__mat__au_cu_hhtp | Nanosheet · Composite Sample · Composite | Higher HAuCl4 loading variant used to show Au-NP agglomeration. | 6 · Figure captions · Figure S5 |
| Cu-HHTP-bulkresearch_0797__mat__cu_hhtp | Powder · Pristine Control · Pristine Framework | Prepared by same aqueous procedure as Cu-HHTP-NSs but without SDS; activated after synthesis. | 2, 4 · Synthesis of Au-NPs/Cu-HHTP-NSs · Fig. 1d; Fig. 2 |
| Cu-HHTP-bulk/GCEresearch_0797__mat__cu_hhtp | Electrode · Pristine Control · Composite | 5 uL of 5 mg mL-1 suspension drop-cast on polished GCE and dried in air.glassy carbon electrode (3 mm) with Nafion/isopropanol suspension | SI text · Preparation of Au-NPs/Cu-HHTP-NSs modified electrode |
| Cu-HHTP-NSsresearch_0797__mat__cu_hhtp | Nanosheet · Composite Component · Pristine Framework | SDS-assisted aqueous synthesis, sonication/exfoliation, freeze-dried and activated.3.59 +/- 0.36 nm | 2-4 · Synthesis of Au-NPs/Cu-HHTP-NSs; Characterization · Fig. 1a-f |
| Cu-HHTP-NSs/GCEresearch_0797__mat__cu_hhtp | Electrode · Pristine Control · Composite | 5 uL of 5 mg mL-1 suspension drop-cast on polished GCE and dried in air.glassy carbon electrode (3 mm) with Nafion/isopropanol suspension | SI text · Preparation of Au-NPs/Cu-HHTP-NSs modified electrode |