Sensing Application — Mitigating lipid biofouling in wearable sweat sensors: A study on conductive MOF-based electrodes with tuned hydrophilicity

Measurement evidence

Sensing Application

Mitigating lipid biofouling in wearable sweat sensors: A study on conductive MOF-based electrodes with tuned hydrophilicity · Liang C., Liu J., Zhang H. et al. · Chemical Engineering Journal · 2025 · 164477

19 measurement groups · 36 results

Reported values remain attached to the sample, method, conditions, extraction quality and source location that produced them.

Wearable sweat sensor system integration

Cu-HHTP electrode · Electrode

Flexible sensing array, signal conditioning, STM32F103CBT6 MCU, DAC8563, TIA, Bluetooth transmission

Context
device architecture
Measurement source
3-4 · Section 2.5 · Schematic 1; Fig. S15
PropertyReported valueNormalised valueUncertaintyOrigin and qualitySource
ADC sample ratefive million samples per secondText
Exact Reported
3 · Section 2.5 · Fig. S15

ELISA validation

Cu-HHTP electrode · Electrode

UA standard curve and raw sweat validation; absorbance at 510 nm

Context
external validation
Measurement source
4; SI 13 · Section 2.5 / Fig. S29 · Fig. S29
PropertyReported valueNormalised valueUncertaintyOrigin and qualitySource
ELISA standard curve R2R2 = 0.99Figure Axis
Approximate
13 · Supplementary Figures · Fig. S29

Chronoamperometry calibrated against ELISA

Cu-HHTP electrode · Electrode

Raw/on-body sweat UA monitoring after purine-rich food intake and during long-term sweat exposure

Context
wearable sweat monitoring
Measurement source
7-8 · Section 3.3 · Fig. 4c-g; Figs. S30-S35
PropertyReported valueNormalised valueUncertaintyOrigin and qualitySource
long-term raw-sweat stabilityMarked as a best value within this paperreliable accuracy and stability after 24 h exposureText
Qualitative
8 · Section 3.3 · Fig. S35
agreement with ELISA in raw sweatMarked as a best value within this paperalmost identical to ELISA testingText
Qualitative
8 · Section 3.3 · Fig. 4d

Chronoamperometry calibrated against ELISA

ZIF-8 electrode · Electrode

Raw/on-body sweat UA monitoring after purine-rich food intake and during long-term sweat exposure

Context
wearable sweat monitoring
Measurement source
7-8 · Section 3.3 · Fig. 4c-g; Figs. S30-S35
PropertyReported valueNormalised valueUncertaintyOrigin and qualitySource
long-term detection accuracy after 2.5 h48.30% after 2.5 hText
Exact Reported
8 · Section 3.3 · Fig. 4g
agreement with ELISA in raw sweatsignificantly underestimated compared to actual valueText
Qualitative
8 · Section 3.3 · Fig. 4d

Chronoamperometry anti-interference test

Cu-HHTP electrode · Electrode

UA challenged with glucose, urea, glycine, CaCl2, NaCl and KCl in sweat matrix

Context
selectivity
Measurement source
11 · Supplementary Figures / Section 3.3 · Fig. S26
PropertyReported valueNormalised valueUncertaintyOrigin and qualitySource
anti-interference responsereliable UA detection without significant interferenceText
Qualitative
7 · Section 3.3 · Fig. S26

Chronoamperometry anti-interference test

Cu-HHTP/OTS electrode · Electrode

UA challenged with glucose, urea, glycine, CaCl2, NaCl and KCl in sweat matrix

Context
selectivity
Measurement source
11 · Supplementary Figures / Section 3.3 · Fig. S26
PropertyReported valueNormalised valueUncertaintyOrigin and qualitySource
anti-interference responsereliable UA detection without significant interferenceText
Qualitative
7 · Section 3.3 · Fig. S26

Chronoamperometry anti-interference test

Cu-THQ electrode · Electrode

UA challenged with glucose, urea, glycine, CaCl2, NaCl and KCl in sweat matrix

Context
selectivity
Measurement source
11 · Supplementary Figures / Section 3.3 · Fig. S26
PropertyReported valueNormalised valueUncertaintyOrigin and qualitySource
anti-interference responsereliable UA detection without significant interferenceText
Qualitative
7 · Section 3.3 · Fig. S26

Chronoamperometry anti-interference test

Ni-HHTP electrode · Electrode

UA challenged with glucose, urea, glycine, CaCl2, NaCl and KCl in sweat matrix

Context
selectivity
Measurement source
11 · Supplementary Figures / Section 3.3 · Fig. S26
PropertyReported valueNormalised valueUncertaintyOrigin and qualitySource
anti-interference responsereliable UA detection without significant interferenceText
Qualitative
7 · Section 3.3 · Fig. S26

Chronoamperometry anti-interference test

ZIF-8 electrode · Electrode

UA challenged with glucose, urea, glycine, CaCl2, NaCl and KCl in sweat matrix

Context
selectivity
Measurement source
11 · Supplementary Figures / Section 3.3 · Fig. S26
PropertyReported valueNormalised valueUncertaintyOrigin and qualitySource
anti-interference responsereliable UA detection without significant interferenceText
Qualitative
7 · Section 3.3 · Fig. S26

Chronoamperometry

Cu-HHTP electrode · Electrode

Multiple sweat-lipid-sweat cycles in wearable patch format

Context
wearable patch durability
Measurement source
7 · Section 3.3 · Fig. 4b
PropertyReported valueNormalised valueUncertaintyOrigin and qualitySource
current retention after multiple sweat-lipid-sweat cyclesMarked as a best value within this paper98%Text
Exact Reported
7 · Section 3.3 · Fig. 4b

Chronoamperometry

Cu-HHTP/OTS electrode · Electrode

Multiple sweat-lipid-sweat cycles in wearable patch format

Context
wearable patch durability
Measurement source
7 · Section 3.3 · Fig. 4b
PropertyReported valueNormalised valueUncertaintyOrigin and qualitySource
current retention after multiple sweat-lipid-sweat cycles47%Text
Exact Reported
7 · Section 3.3 · Fig. 4b

Chronoamperometry

Cu-THQ electrode · Electrode

Multiple sweat-lipid-sweat cycles in wearable patch format

Context
wearable patch durability
Measurement source
7 · Section 3.3 · Fig. 4b
PropertyReported valueNormalised valueUncertaintyOrigin and qualitySource
current retention after multiple sweat-lipid-sweat cycles58%Text
Exact Reported
7 · Section 3.3 · Fig. 4b

Chronoamperometry

Ni-HHTP electrode · Electrode

Multiple sweat-lipid-sweat cycles in wearable patch format

Context
wearable patch durability
Measurement source
7 · Section 3.3 · Fig. 4b
PropertyReported valueNormalised valueUncertaintyOrigin and qualitySource
current retention after multiple sweat-lipid-sweat cycles63%Text
Exact Reported
7 · Section 3.3 · Fig. 4b

Chronoamperometry

ZIF-8 electrode · Electrode

Multiple sweat-lipid-sweat cycles in wearable patch format

Context
wearable patch durability
Measurement source
7 · Section 3.3 · Fig. 4b
PropertyReported valueNormalised valueUncertaintyOrigin and qualitySource
current retention after multiple sweat-lipid-sweat cycles20%Text
Exact Reported
7 · Section 3.3 · Fig. 4b

Differential pulse voltammetry (DPV)

Cu-HHTP electrode · Electrode

Artificial sweat pH 5.5; three-electrode setup; step 4 mV, width 0.2 s, period 0.5 s, amplitude 50 mV

Geometry
MOF working electrode, Ag/AgCl reference, Pt counter
Context
UA sensing in artificial sweat
Measurement source
3,7 · Sections 2.5 and 3.3 · Fig. S16; Fig. S21
PropertyReported valueNormalised valueUncertaintyOrigin and qualitySource
DPV calibration concentration range0-500 uMVisual Estimate
Approximate
7-8 · Supplementary Figures · Fig. S16
UA limit of detectionMarked as a best value within this paper0.62 uMText
Exact Reported
7 · Section 3.3 · Figs. S21-S25
LOD fitting concentration range0-60 uMCaption
Exact Reported
9-11 · Supplementary Figures · Fig. S21
UA sensitivityMarked as a best value within this paper119.5 uA mM^-1 cm^-2Text
Exact Reported
7 · Section 3.3 · Figs. S16-S20

Differential pulse voltammetry (DPV)

Cu-HHTP/OTS electrode · Electrode

Artificial sweat pH 5.5; three-electrode setup; step 4 mV, width 0.2 s, period 0.5 s, amplitude 50 mV

Geometry
MOF working electrode, Ag/AgCl reference, Pt counter
Context
UA sensing in artificial sweat
Measurement source
3,7 · Sections 2.5 and 3.3 · Fig. S19; Fig. S24
PropertyReported valueNormalised valueUncertaintyOrigin and qualitySource
DPV calibration concentration range0-280 uMVisual Estimate
Approximate
7-8 · Supplementary Figures · Fig. S19
UA limit of detection1.08 uMText
Exact Reported
7 · Section 3.3 · Figs. S21-S25
LOD fitting concentration range0-70 uMCaption
Exact Reported
9-11 · Supplementary Figures · Fig. S24
UA sensitivity32.8 uA mM^-1 cm^-2Text
Exact Reported
7 · Section 3.3 · Figs. S16-S20

Differential pulse voltammetry (DPV)

Cu-THQ electrode · Electrode

Artificial sweat pH 5.5; three-electrode setup; step 4 mV, width 0.2 s, period 0.5 s, amplitude 50 mV

Geometry
MOF working electrode, Ag/AgCl reference, Pt counter
Context
UA sensing in artificial sweat
Measurement source
3,7 · Sections 2.5 and 3.3 · Fig. S18; Fig. S23
PropertyReported valueNormalised valueUncertaintyOrigin and qualitySource
DPV calibration concentration range0-530 uMVisual Estimate
Approximate
7-8 · Supplementary Figures · Fig. S18
UA limit of detection2.76 uMText
Exact Reported
7 · Section 3.3 · Figs. S21-S25
LOD fitting concentration range10-120 uMCaption
Exact Reported
9-11 · Supplementary Figures · Fig. S23
UA sensitivity50.8 uA mM^-1 cm^-2Text
Exact Reported
7 · Section 3.3 · Figs. S16-S20

Differential pulse voltammetry (DPV)

Ni-HHTP electrode · Electrode

Artificial sweat pH 5.5; three-electrode setup; step 4 mV, width 0.2 s, period 0.5 s, amplitude 50 mV

Geometry
MOF working electrode, Ag/AgCl reference, Pt counter
Context
UA sensing in artificial sweat
Measurement source
3,7 · Sections 2.5 and 3.3 · Fig. S17; Fig. S22
PropertyReported valueNormalised valueUncertaintyOrigin and qualitySource
DPV calibration concentration range0-430 uMVisual Estimate
Approximate
7-8 · Supplementary Figures · Fig. S17
LOD fitting concentration range10-80 uMCaption
Exact Reported
9-11 · Supplementary Figures · Fig. S22
UA limit of detection3.03 uMText
Exact Reported
7 · Section 3.3 · Figs. S21-S25
UA sensitivity58.9 uA mM^-1 cm^-2Text
Exact Reported
7 · Section 3.3 · Figs. S16-S20

Differential pulse voltammetry (DPV)

ZIF-8 electrode · Electrode

Artificial sweat pH 5.5; three-electrode setup; step 4 mV, width 0.2 s, period 0.5 s, amplitude 50 mV

Geometry
MOF working electrode, Ag/AgCl reference, Pt counter
Context
UA sensing in artificial sweat
Measurement source
3,7 · Sections 2.5 and 3.3 · Fig. S20; Fig. S25
PropertyReported valueNormalised valueUncertaintyOrigin and qualitySource
DPV calibration concentration range0-550 uMVisual Estimate
Approximate
7-8 · Supplementary Figures · Fig. S20
LOD fitting concentration range0-60 uMCaption
Exact Reported
9-11 · Supplementary Figures · Fig. S25
UA limit of detection2.89 uMText
Exact Reported
7 · Section 3.3 · Figs. S21-S25
UA sensitivity39.3 uA mM^-1 cm^-2Text
Exact Reported
7 · Section 3.3 · Figs. S16-S20