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MTT assay and related biological assays

finely ground/as-synthesised compound 1 powder · Powder

MTT, trypan blue, cell-cycle, annexin V-FITC/PI, ROS, caspase 3/7, DAPI and JC1 biological assays; SI reports cell culture and assay protocols.

Atmosphere: 37 deg C humidified incubator containing 5% CO2 for cell culture
Context: pristine framework biological application
Measurement source: rendered pages 5-9 / article pp.19941-19945 · Cytotoxicity Studies · Figures 10-13

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
caspase 3 activity increase at 10 uM	1.32 times	—	—	Text Exact Reported	rendered page 8 / article p.19944 · Apoptotic Cell Death · Figure 10e
caspase 3 activity increase at 20 uM	1.82 times	—	—	Text Exact Reported	rendered page 8 / article p.19944 · Apoptotic Cell Death · Figure 10e
caspase 3 activity increase at 30 uMMarked as a best value within this paper	2.26 times	—	—	Text Exact Reported	rendered page 8 / article p.19944 · Apoptotic Cell Death · Figure 10e
IC50 HCT-116	26.06 +/- 3.48 uM	—	+/- 3.48 uM	Text Exact Reported	rendered page 5 / article p.19941 · Cytotoxicity Studies · Figure 10
IC50 HeLa	24.43 +/- 2.02 uM	—	+/- 2.02 uM	Text Exact Reported	rendered page 5 / article p.19941 · Cytotoxicity Studies · Figure 10
IC50 HepG2	44.28 +/- 3.04 uM	—	+/- 3.04 uM	Text Exact Reported	rendered page 5 / article p.19941 · Cytotoxicity Studies · Figure 10
IC50 MDA-MB-231Marked as a best value within this paper	19.43 +/- 1.36 uM	—	+/- 1.36 uM	Text Exact Reported	rendered page 5 / article p.19941 · Cytotoxicity Studies · Figure 10

finely ground/as-synthesised compound 1 powder · Powder

30-800 deg C in N2 atmosphere; main text and SI thermal-analysis section state 10 deg C min-1, while SI general methods states 2 deg C/min.

Atmosphere: N2
Context: pristine framework
Measurement source: rendered page 3 / article p.19939 · Results and Discussion · Figure S2

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
calculated final residue	ZnO calculated 17.62%	—	—	Text Exact Reported	rendered page 3 / article p.19939 · Results and Discussion · Figure S2
experimental final residue	ZnO experimental 17.89%	—	—	Text Exact Reported	rendered page 3 / article p.19939 · Results and Discussion · Figure S2
thermal stability threshold	stable up to 210 deg C	—	—	Text Rounded Reported	rendered page 3 / article p.19939 · Results and Discussion · Figure S2