Sensing Application — Detection of Ascorbic Acid by Two-Dimensional Conductive Metal-Organic Framework-Based Electrochemical Sensors

5 measurement groups · 36 results

Reported values remain attached to the sample, method, conditions, extraction quality and source location that produced them.

differential pulse voltammetry (DPV)

Voltammetry

Cu3(HHTP)2/SPE · Electrode

0.1 mol/L PBS; DPV range -1 to 1 V; potential increment 0.005 V; pulse amplitude 0.05 V; pulse width 0.3 s; AA concentration range 25-1645 umol/L.

Geometry: screen-printed electrode sensor
Context: Cu3(HHTP)2 composite electrode
Measurement source: 5,8 · 2. Results and Discussion; 3.2.4. Electrochemical Test · Figure 4a,b

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
AA calibration R2	R2 = 0.99	—	—	Text Exact Reported	5 · 2. Results and Discussion · Figure 4b
AA detection linear range upper boundMarked as a best value within this paper	1645 umol/L	1645 umol/L	—	Text Exact Reported	5 · 2. Results and Discussion · Figure 4a,b
AA detection linear range lower boundMarked as a best value within this paper	25 umol/L	25 umol/L	—	Text Exact Reported	5 · 2. Results and Discussion · Figure 4a,b
AA calibration slope	y = -0.0345x - 2 x 10-6	—	—	Text Exact Reported	5 · 2. Results and Discussion · Figure 4b
AA detection limitMarked as a best value within this paper	2.44 umol/L (S/N = 3)	2.44 umol/L	S/N = 3	Text Exact Reported	8 · 4. Conclusions · Figure 4a,b

parallel electrode uncertainty experiment

Cu3(HHTP)2/SPE · Electrode

Twelve Cu3(HHTP)2/SPE sensors prepared to detect AA; average current and electrode uncertainty calculated by guideline.

Geometry: screen-printed electrode sensor
Context: Cu3(HHTP)2 composite electrode reproducibility
Measurement source: 1 · Supplementary Materials · Table S1

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
parallel sensor 1 oxidation peak current	9.44 uA	9.44 uA	—	SI Table Exact Reported	1 · Supplementary Materials · Table S1
parallel sensor 2 oxidation peak current	10.80 uA	10.8 uA	—	SI Table Exact Reported	1 · Supplementary Materials · Table S1
parallel sensor 3 oxidation peak current	10.99 uA	10.99 uA	—	SI Table Exact Reported	1 · Supplementary Materials · Table S1
parallel sensor 4 oxidation peak current	11.10 uA	11.1 uA	—	SI Table Exact Reported	1 · Supplementary Materials · Table S1
parallel sensor 5 oxidation peak current	10.78 uA	10.78 uA	—	SI Table Exact Reported	1 · Supplementary Materials · Table S1
parallel sensor 6 oxidation peak current	10.70 uA	10.7 uA	—	SI Table Exact Reported	1 · Supplementary Materials · Table S1
parallel sensor 7 oxidation peak current	11.57 uA	11.57 uA	—	SI Table Exact Reported	1 · Supplementary Materials · Table S1
parallel sensor 8 oxidation peak current	10.32 uA	10.32 uA	—	SI Table Exact Reported	1 · Supplementary Materials · Table S1
parallel sensor 9 oxidation peak current	11.65 uA	11.65 uA	—	SI Table Exact Reported	1 · Supplementary Materials · Table S1
parallel sensor 10 oxidation peak current	10.50 uA	10.5 uA	—	SI Table Exact Reported	1 · Supplementary Materials · Table S1
parallel sensor 11 oxidation peak current	10.28 uA	10.28 uA	—	SI Table Exact Reported	1 · Supplementary Materials · Table S1
parallel sensor 12 oxidation peak current	10.58 uA	10.58 uA	—	SI Table Exact Reported	1 · Supplementary Materials · Table S1
parallel sensor average current	I = 10.725 uA	10.725 uA	—	Calculated From Reported Exact Reported	8 · 3.2.6. Electrode Uncertainty Experiments · Table S1
electrode uncertaintyMarked as a best value within this paper	0.171	—	—	Text Exact Reported	6 · 2. Results and Discussion · Table S1

DPV interference/selectivity test

Voltammetry

Cu3(HHTP)2/SPE · Electrode

200 uM AA with 2 mM KCl, Glu, Gly, and CA, respectively; interferences are 10-times AA concentration.

Geometry: screen-printed electrode sensor
Context: Cu3(HHTP)2 composite electrode
Measurement source: 5-6 · 2. Results and Discussion · Figure 4c,d; Figure S5

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
interference concentration	2 mM interferences; 10-times interference	2000 umol/L	—	Caption Exact Reported	6 · Figure 4 caption · Figure 4c,d
AA plus CA DPV signal relative to pure AA	1.2 times higher than pure AA	—	—	Text Exact Reported	5 · 2. Results and Discussion · Figure 4c,d
selectivity against Glu, KCl, and Gly	almost no change in DPV current response	—	—	Text Qualitative	5-6 · 2. Results and Discussion · Figure 4c,d

standard addition recovery in mouse serum

Cu3(HHTP)2/SPE · Electrode

Cu3(HHTP)2/SPE used to detect AA in actual mouse serum samples at 25, 55, and 285 umol/L.

Geometry: screen-printed electrode sensor
Context: Cu3(HHTP)2 composite electrode in biological sample application
Measurement source: 6 · 2. Results and Discussion · Table 1

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
serum AA detected value at 25 umol/L	24.7 umol/L	24.7 umol/L	—	Table Exact Reported	6 · Table 1 · Table 1
serum AA recovery at 25 umol/L	98.6%	0.986 fraction	—	Table Exact Reported	6 · Table 1 · Table 1
serum AA RSD at 25 umol/L	4.87%	—	—	Table Exact Reported	6 · Table 1 · Table 1
serum AA detected value at 285 umol/L	282.2 umol/L	282.2 umol/L	—	Table Exact Reported	6 · Table 1 · Table 1
serum AA recovery at 285 umol/LMarked as a best value within this paper	99.0%	0.99 fraction	—	Table Exact Reported	6 · Table 1 · Table 1
serum AA RSD at 285 umol/LMarked as a best value within this paper	0.67%	—	—	Table Exact Reported	6 · Table 1 · Table 1
serum AA detected value at 55 umol/L	53.9 umol/L	53.9 umol/L	—	Table Exact Reported	6 · Table 1 · Table 1
serum AA recovery at 55 umol/L	98.0%	0.98 fraction	—	Table Exact Reported	6 · Table 1 · Table 1
serum AA RSD at 55 umol/L	4.08%	—	—	Table Exact Reported	6 · Table 1 · Table 1

current retention over time

Cu3(HHTP)2/SPE · Electrode

AA response current of Cu3(HHTP)2/SPE evaluated over first, fifth, and tenth day in SI Figure S5; main text reports 86% retention after 5 days but appears to reference a non-present Figure S6.

Geometry: screen-printed electrode sensor
Context: Cu3(HHTP)2 composite electrode
Measurement source: 3 · Figure S5 caption · Figure S5

Property	Reported value	Normalised value	Uncertainty	Origin and quality	Source
AA response current on fifth day	about 4.15 uA from SI Figure S5b bar	4.15 uA	—	Visual Estimate Approximate	3 · Supplementary Materials · Figure S5b
AA response current on first dayMarked as a best value within this paper	about 4.35 uA from SI Figure S5b bar	4.35 uA	—	Visual Estimate Approximate	3 · Supplementary Materials · Figure S5b
AA response current on tenth day	about 3.75 uA from SI Figure S5b bar	3.75 uA	—	Visual Estimate Approximate	3 · Supplementary Materials · Figure S5b
tenth-day current retention estimated from SI bars	about 86% of first-day current from Figure S5b bars	0.86 fraction	—	Calculated From Reported Approximate	3 · Supplementary Materials · Figure S5b
5-day current retentionMarked as a best value within this paper	86% of initial current after 5 days	0.86 fraction	—	Text Exact Reported	6 · 2. Results and Discussion · Figure S5/S6 inconsistency