Xu L., Lou W., Xu F. et al. · Materials Chemistry Frontiers · 2025 · 2018-2030
Open a family to keep every result attached to its sample, method and conditions.
Paraphrased for this database from the authors’ stated interpretations — never quoted verbatim — and kept separate from reported measurements.
The bipolar electrode design is claimed to maintain simulated temperature below 45 C even at 3000 V cm^-1, reducing risk of thermal damage.
Caveat: Temperature result is simulation-derived and reported as a threshold.
2022 · 3.1 Design and simulation experiments · Fig. 1; Fig. S4 · Linked to 1 structured result
The authors state that the combination therapy is still at an initial stage and requires extensive preclinical data before clinical translation.
2026-2028 · 3.6 and Conclusions
Ni3(HITP)2@PDA is proposed to alter the local conductive environment, increase cellular conductivity, amplify ROS, and enhance bipolar IRE tumour-cell killing.
Caveat: Mechanistic claims are based on application assays and qualitative imaging rather than direct electrical mapping in tissue.
2025 · 3.5 In vitro therapeutic mechanism · Fig. 4; Fig. S18-S19 · Linked to 3 structured results
Ni3(HITP)2@PDA formation is supported by microscopy, EDS nitrogen mapping, retained XRD crystallinity, FTIR PDA bands, and XPS composition changes.
Caveat: No raw spectra or crystallographic files were included in the assigned text layer.
2022 · 3.3 Characterization of conductive MOF · Fig. 2; Fig. S12 · Linked to 7 structured results
PDA surface functionalisation improves the dispersibility of Ni3(HITP)2, as reflected by lower PDI.
Caveat: PDI values are reported directly, but the SI does not provide raw DLS distributions beyond the figure.
2022 · 3.3 Characterization of conductive MOF · Fig. S11 · Linked to 2 structured results
PDA coating does not eliminate conductivity of the Ni3(HITP)2 framework; solution conductivity increases with concentration and remains comparable to pristine Ni3(HITP)2 in SI Fig. S14.
Caveat: Conductivity values are figure-axis estimates from solution measurements, not exact tabulated solid-state conductivities.
2023 · 3.3 Characterization of conductive MOF · Fig. 2i; Fig. S14 · Linked to 4 structured results
Names and aliases are kept exactly within the paper’s own identity model.
| Material | Composition | Structure context | Source |
|---|---|---|---|
| bipolar IRE electrode | Not specified | unknown · Model SystemDevice model integrating cathode and anode in one electrode, with two 3 mm exposed ends separated by 4 mm insulation. | 2021 · 3.1 Design and simulation experiments of bipolar electrode · Fig. S1 |
| Ni3(HITP)2Browse family: Ni₃(HITP)₂ / Ni–HITP | Ni3(HITP)2Ni · HITP | 2D · PristineSheet-like conductive MOF; crystallinity retained after PDA coating according to XRD comparison. | 2019 · 2.1 Materials and chemicals |
| Ni3(HITP)2@PDABrowse family: Ni₃(HITP)₂ / Ni–HITP | Ni3(HITP)2@PDANi · HITP plus polydopamine coating | 2D · CompositePDA-coated Ni3(HITP)2 nanoparticles; SEM/TEM showed conformal PDA coating and XRD retained crystallinity. | 2022-2023 · 3.3 Characterization of conductive MOF · Fig. 2 |
Sample form, processing state and composition status define the context for measurements.
| Sample | Form and role | Processing and geometry | Source |
|---|---|---|---|
| Bipolar IRE electrode computational modelresearch_0874__mat__bipolar_ire_electrode | Model · Model System · Model | COMSOL tissue/electrode model | 2019 · 2.2 Design and simulation of bipolar electrodes |
| Bipolar IRE + Ni3(HITP)2@PDA treated KPC/tumour modelresearch_0874__mat__ni3_hitp2_pda | Model · Model System · Composite | Ni3(HITP)2@PDA added or injected 2 h before bipolar IRE ablationKPC cells or BALB/c nude mouse tumour model | 2020 · 2.8-2.9 In vitro/in vivo evaluation |
| Ni3(HITP)2@PDA nanoparticlesresearch_0874__mat__ni3_hitp2_pda | Powder · Composite Sample · Composite | PDA-coated particles washed and dried | 2019 · 2.7 Preparation and characterization of Ni3(HITP)2@PDA |
| Purchased Ni3(HITP)2 powderresearch_0874__mat__ni3_hitp2 | Powder · Pristine Control · Pristine Framework | as-purchased powder | 2019 · 2.1 Materials and chemicals |