Sensing Application — In-situ growth of high-crystallinity M3(hexaaminotriphenylene)2 (M = Co, Ni) thin film for field-effect transistor-based glucose biosensor

Measurement evidence

Sensing Application

In-situ growth of high-crystallinity M3(hexaaminotriphenylene)2 (M = Co, Ni) thin film for field-effect transistor-based glucose biosensor · Tan P., Shen S., Luo Y. et al. · Chinese Chemical Letters · 2026 · 111636

7 measurement groups · 24 results

Reported values remain attached to the sample, method, conditions, extraction quality and source location that produced them.

FET glucose sensing by monitoring drain current

Co/Ni-HITP-GA-FET sensor · Electrode

GA-only Co/Ni-HITP-GA-FET exposed to glucose solutions; PBS blank

Temperature
room temperature
Atmosphere
1x PBS liquid cell
Geometry
fixed Vgs = -0.1 V and Vds = -0.1 V
Context
GA-only control
Measurement source
5 · Glucose sensing performance · Fig. 5c
PropertyReported valueNormalised valueUncertaintyOrigin and qualitySource
glucose response with GA onlynot a significant current responseText
Qualitative
5 · Glucose sensing performance · Fig. 5c

FET glucose sensing by monitoring drain current

Co/Ni-HITP-GA-GOX-FET sensor · Electrode

15 uL PBS blank followed by 15 uL glucose solutions from 10 nmol/L to 10 mmol/L; Vgs = -0.1 V, Vds = -0.1 V, room temperature

Temperature
room temperature
Atmosphere
1x PBS liquid cell
Geometry
electrolyte-gated FET with Co/Ni-HITP-GA-GOX channel
Context
GA/GOX-modified biosensor sample
Measurement source
Sensing test methods · Fig. 5d-e
PropertyReported valueNormalised valueUncertaintyOrigin and qualitySource
glucose detection range lower boundMarked as a best value within this paper10 nmol/LText
Exact Reported
5 · Glucose sensing performance · Fig. 5d; Table S1 discussion
glucose detection range upper boundMarked as a best value within this paper10 mmol/LText
Exact Reported
5 · Glucose sensing performance · Fig. 5d; Table S1 discussion
linear fit intercept-3.76Text
Exact Reported
5 · Glucose sensing performance · Fig. 5e
linear fit slopey = -0.39x - 3.76; slope -0.39Text
Exact Reported
5 · Glucose sensing performance · Fig. 5e
linear glucose range lower boundMarked as a best value within this paper10 nmol/LText
Exact Reported
5 · Glucose sensing performance · Fig. 5e
linear glucose range upper boundMarked as a best value within this paper5 mmol/LText
Exact Reported
5 · Glucose sensing performance · Fig. 5e
linear correlation coefficient R2Marked as a best value within this paperR2 = 0.996Text
Exact Reported
5 · Glucose sensing performance · Fig. 5e
current response at 10 mmol/L glucoseMarked as a best value within this paperabout 3.30 uAText
Approximate
5 · Glucose sensing performance · Fig. 5d
glucose sensitivityMarked as a best value within this paper39 uA (mol/L)-1 mm-2Text
Exact Reported
5 · Glucose sensing performance · Table S1 discussion

control FET glucose sensing

Co-HITP-GA-GOX-FET sensor · Electrode

Ni-HITP-GA-GOX-FET, Co-HITP-GA-GOX-FET and Co/Ni-HITP(water)-GA-GOX-FET controls fabricated by same modification method

Temperature
room temperature
Atmosphere
1x PBS liquid cell
Geometry
FET sensors
Context
monometallic and water-phase controls
Measurement source
5 · Glucose sensing performance · Fig. S5
PropertyReported valueNormalised valueUncertaintyOrigin and qualitySource
Co-HITP-GA-GOX-FET total current response from 10 nmol/L to 10 mmol/Labout 1.23 uAText
Approximate
5 · Glucose sensing performance · Fig. S5b
Co/Ni-HITP(water)-GA-GOX-FET response qualitysatisfactory linearity but relatively small absolute current changeText
Qualitative
5 · Glucose sensing performance · Fig. S5c
Ni-HITP-GA-GOX-FET glucose response trendsignificant current fluctuations, not linearText
Qualitative
5 · Glucose sensing performance · Fig. S5a

selectivity test by FET drain-current response

Co/Ni-HITP-GA-GOX-FET sensor · Electrode

10 nmol/L glucose, 1 umol/L fructose/sucrose/ascorbic acid interferences, then 100 nmol/L glucose

Temperature
room temperature
Atmosphere
1x PBS liquid cell
Geometry
Co/Ni-HITP-GA-GOX-FET
Context
GA/GOX-modified biosensor sample
Measurement source
5 · Glucose sensing performance · Fig. 5f
PropertyReported valueNormalised valueUncertaintyOrigin and qualitySource
selectivity against fructose, sucrose and ascorbic acid1 umol/L interferents gave only weak response, while 10 and 100 nmol/L glucose gave obvious/significant responsesText
Qualitative
5 · Glucose sensing performance · Fig. 5f

long-term stability and reusability FET sensing

Co/Ni-HITP-GA-GOX-FET sensor · Electrode

Multiple devices stored at 0-4 deg C and tested at 24 h intervals; same sensor retested at two-day intervals

Atmosphere
stored at 0-4 deg C; tested in PBS liquid cell
Geometry
Co/Ni-HITP-GA-GOX-FET
Context
GA/GOX-modified biosensor sample
Measurement source
5 · Glucose sensing performance · Fig. 5g-i; Fig. S6
PropertyReported valueNormalised valueUncertaintyOrigin and qualitySource
high-sensitivity retention durationup to two days post-modificationText
Exact Reported
5 · Glucose sensing performance · Fig. 5g-h
reusability current response day 0Marked as a best value within this paper2.89 uAText
Exact Reported
5 · Glucose sensing performance · Fig. S6
reusability current-response decrease on day 23.81 %Text
Exact Reported
5 · Glucose sensing performance · Fig. S6
reusability current response day 22.78 uAText
Exact Reported
5 · Glucose sensing performance · Fig. S6
reusability current-response decrease on day 447.10 %Text
Exact Reported
5 · Glucose sensing performance · Fig. S6
reusability current response day 41.53 uAText
Exact Reported
5 · Glucose sensing performance · Fig. S6
response to 10 nmol/L glucose in five repeat testsabout 600 nAText
Approximate
5 · Glucose sensing performance · Fig. 5i

FET glucose sensing by monitoring drain current

Co/Ni-HITP-FET sensor without modification · Electrode

Unmodified Co/Ni-HITP-FET exposed to glucose solutions; PBS blank

Temperature
room temperature
Atmosphere
1x PBS liquid cell
Geometry
fixed Vgs = -0.1 V and Vds = -0.1 V
Context
pristine device control
Measurement source
5 · Glucose sensing performance · Fig. 5b
PropertyReported valueNormalised valueUncertaintyOrigin and qualitySource
glucose response without GOXnot a significant current responseText
Qualitative
5 · Glucose sensing performance · Fig. 5b

SI Table S1 literature comparison of glucose-sensor detection range

Co/Ni-HITP-GA-GOX-FET sensor · Electrode

Comparison table reports this work as bimetallic Co/Ni-HITP FET with detection range 0.01-10000 umol/L

Geometry
Co/Ni-HITP-GA-GOX-FET glucose biosensor
Context
GA/GOX-modified biosensor sample
Measurement source
S-11 · Supporting information · Table S1
PropertyReported valueNormalised valueUncertaintyOrigin and qualitySource
Table S1 this-work detection range lower boundMarked as a best value within this paper0.01 umol/LSI Table
Exact Reported
S-11 · Supporting information · Table S1
Table S1 this-work detection range upper boundMarked as a best value within this paper10000 umol/LSI Table
Exact Reported
S-11 · Supporting information · Table S1